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Carbon ion radiotherapy for treatment of prostate cancer and subsequent outcomes after biochemical failure
https://repo.qst.go.jp/records/45994
https://repo.qst.go.jp/records/459949e5f59be-9de8-4da8-a73e-29a2af3010ef
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2011-02-04 | |||||
| タイトル | ||||||
| タイトル | Carbon ion radiotherapy for treatment of prostate cancer and subsequent outcomes after biochemical failure | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Shimazaki, Jun
× Shimazaki, Jun× Tsuji, Hiroshi× Ishikawa, Hitoshi× Okada, Tohru× Akakura, Kouichirou× Harada, Masaoki× Tsujii, Hirohiko× et.al× 島崎 淳× 辻 比呂志× 石川 仁× 岡田 徹× 赤倉 功一郎× 原田 昌興× 辻井 博彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Abstract BACKGROUND/AIM: Carbon ion radiotherapy is expected to be suitable to treat localized prostate cancer because it yields great biological and physical effects. The aim of this study was to examine long-term results and subsequent outcomes after biochemical failure. PATIENTS AND METHODS: A total of 254 patients were treated from the beginning of 2003 and followed through 2009. Long-term hormone therapy was also used for some intermediate-risk and high-risk patients. RESULTS: Among the patients examined, 54 patients experienced biochemical failure. Failure-free survival was 76%, 91% and 76% at eight years in low-risk, intermediate-risk and high-risk patients, respectively. Clinical progression occurred only in high-risk patients, with 89% progression-free survival at eight years. After biochemical failure, diseases of most patients were well controlled by salvage therapy but twelve high-risk patients (5%) died of prostate cancer. CONCLUSION: Carbon ion radiotherapy had an excellent effect on localized prostate cancer. Factors influencing salvage therapy included PSA kinetics and duration between radiation and failure. |
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| 書誌情報 |
Anticancer Research 巻 30, 号 12, p. 5105-5111, 発行日 2010-12 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0250-7005 | |||||
