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Colitis associated with Clostridium difficile in specific-pathogen-free C3H-scid mice
https://repo.qst.go.jp/records/45004
https://repo.qst.go.jp/records/45004f5cf856a-5545-46eb-b9ee-d3a9f60ebc15
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-10-26 | |||||
| タイトル | ||||||
| タイトル | Colitis associated with Clostridium difficile in specific-pathogen-free C3H-scid mice | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kawano, Akihiro
× Kawano, Akihiro× Ikeda, Manabu× Iritani, Riichirou× Kinoshita, Akiko× Watanabe, Kaori× Hayao, Tatsuo× Kokubo, Toshiaki× Matsushita, Satoru× 河野 明広× 池田 学× 入谷 理一郎× 舘野 香里× 早尾 辰雄× 小久保 年章× 松下 悟 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Soft feces and a decreased delivery rate were observed in a specific pathogen-free (SPF) C3H-scid mouse breeding colony. Grossly, the ceca were shrunken and edematous in the affected mice. Histopathologically, severe edema in the cecal submucosa as well as infiltration of inflammatory cells in the lamina propria and submucosa of the ceca and colon were observed. No pathogenic microorganisms were detected by the routine microbiological tests. By anaerobic bacterial-examination, Clostridium (C.) difficile with toxin A was isolated from the cecal contents of the affected mice. The present mice were diagnosed as C. difficile-associated colitis. This case appears to be the first report of natural infection with C. difficile in SPF mice with clinical signs. | |||||
| 書誌情報 |
Journal of Veterinary Medical Science 巻 69, 号 9, p. 973-975, 発行日 2007-09 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0916-7250 | |||||
