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  1. 原著論文

Colitis associated with Clostridium difficile in specific-pathogen-free C3H-scid mice

https://repo.qst.go.jp/records/45004
https://repo.qst.go.jp/records/45004
f5cf856a-5545-46eb-b9ee-d3a9f60ebc15
Item type 学術雑誌論文 / Journal Article(1)
公開日 2007-10-26
タイトル
タイトル Colitis associated with Clostridium difficile in specific-pathogen-free C3H-scid mice
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Kawano, Akihiro

× Kawano, Akihiro

WEKO 446957

Kawano, Akihiro

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Ikeda, Manabu

× Ikeda, Manabu

WEKO 446958

Ikeda, Manabu

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Iritani, Riichirou

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WEKO 446959

Iritani, Riichirou

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Kinoshita, Akiko

× Kinoshita, Akiko

WEKO 446960

Kinoshita, Akiko

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Watanabe, Kaori

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WEKO 446961

Watanabe, Kaori

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Hayao, Tatsuo

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WEKO 446962

Hayao, Tatsuo

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Kokubo, Toshiaki

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WEKO 446963

Kokubo, Toshiaki

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Matsushita, Satoru

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WEKO 446964

Matsushita, Satoru

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河野 明広

× 河野 明広

WEKO 446965

en 河野 明広

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池田 学

× 池田 学

WEKO 446966

en 池田 学

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入谷 理一郎

× 入谷 理一郎

WEKO 446967

en 入谷 理一郎

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舘野 香里

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WEKO 446968

en 舘野 香里

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早尾 辰雄

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WEKO 446969

en 早尾 辰雄

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小久保 年章

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en 小久保 年章

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松下 悟

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WEKO 446971

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内容記述タイプ Abstract
内容記述 Soft feces and a decreased delivery rate were observed in a specific pathogen-free (SPF) C3H-scid mouse breeding colony. Grossly, the ceca were shrunken and edematous in the affected mice. Histopathologically, severe edema in the cecal submucosa as well as infiltration of inflammatory cells in the lamina propria and submucosa of the ceca and colon were observed. No pathogenic microorganisms were detected by the routine microbiological tests. By anaerobic bacterial-examination, Clostridium (C.) difficile with toxin A was isolated from the cecal contents of the affected mice. The present mice were diagnosed as C. difficile-associated colitis. This case appears to be the first report of natural infection with C. difficile in SPF mice with clinical signs.
書誌情報 Journal of Veterinary Medical Science

巻 69, 号 9, p. 973-975, 発行日 2007-09
ISSN
収録物識別子タイプ ISSN
収録物識別子 0916-7250
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