WEKO3
アイテム
Late Rectal Complications Evaluated by computed tomography-Based Dose Calculations in Patients with Cervical carcinoma Undergoing high-Dose-rate Brachytherapy
https://repo.qst.go.jp/records/44998
https://repo.qst.go.jp/records/44998fb6c66ee-b5c8-4ee0-b3d3-46ab9c134071
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-10-16 | |||||
| タイトル | ||||||
| タイトル | Late Rectal Complications Evaluated by computed tomography-Based Dose Calculations in Patients with Cervical carcinoma Undergoing high-Dose-rate Brachytherapy | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Noda, Shinei
× Noda, Shinei× Ohno, Tatsuya× Kato, Shingo× Ishii, Takayoshi× Saitou, Osami× Wakatuki, Masaru× Tamaki, Tomoaki× Watanabe, Kazuhiro× Nakano, Takashi× Tsujii, Hirohiko× 大野 達也× 加藤 眞吾× 石居 隆義× 斉藤 収三× 若月 優× 田巻 倫明× 渡邊 和洋× 中野 隆史× 辻井 博彦 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: To investigate the efficacy of dose calculations at the computed tomography (CT)-based rectal point (CTRP) as a predictive factor for late rectal complications in patients with cervical carcinoma who were treated with a combination of high-dose-rate intracavitary brachytherapy and external beam radiotherapy. \nMethods and Materials: Ninety-two patients with uterine cervical carcinoma undergoing definitive radiotherapy alone were retrospectively analyzed. The median follow-up time for all patients was 32 months (range, 13–60 months). The cumulative biologically effective dose (BED) was calculated at the rectal reference point as defined by the International Commission on Radiation Units and Measurements Report 38 (BEDRP) and at the CTRP (BEDCTRP). Late rectal complications were recorded according to the Radiation Therapy Oncology Group grading system. \nResults: The late rectal complications were distributed as follows: Grade 0, 68 patients (74%); Grade 1, 20 patients (22%); Grade 2, 4 patients (4%). Univariate analysis showed that BEDRP, BEDCTRP, RP dose/point A dose ratio, and CTRP dose/point A dose ratio were significantly correlated with late rectal complications (p < 0.05). On multivariate analysis, patients with a rectal BEDCTRP ≥140 Gy3 presented with significantly greater frequency of rectal complications (p = 0.031). \nConclusions: The present results suggest that BEDCTRP is a useful predictive factor for late rectal complications. |
|||||
| 書誌情報 |
International Journal of Radiation Oncology Biology Physics 巻 69, 号 1, p. 118-124, 発行日 2007-02 |
|||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0360-3016 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.ijrobp.2007.02.027 | |||||
