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High levels of melanin-related metabolites in plasma from pink-eyed dilution mice
https://repo.qst.go.jp/records/44858
https://repo.qst.go.jp/records/448580a25c52a-38de-494b-9bdb-edecc2ebd4c1
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-05-29 | |||||
| タイトル | ||||||
| タイトル | High levels of melanin-related metabolites in plasma from pink-eyed dilution mice | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Wakamatsu, Kazumasa
× Wakamatsu, Kazumasa× Hirobe, Tomohisa× Ito, Shosuke× 廣部 知久 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Pink-eyed dilution (p/p) mice produce greatly reduced (less than 1/10 that of black) levels of eumelanic pigment in follicular melanocytes in vivo. However, in the present study the plasma levels of 6H5MI2C and 5-S-CD in p/p mice at 7.5 days were 9-fold and 4-fold greater than in black mice. These results may appear surprising at first but are consistent with our finding that cultured p/p melanocytes fail to accumulate eumelanin and pheomelanin in the cells but release most of them (more than 90%) to the culture medium. The dramatic increases in the plasma levels of 6H5MI2C and 5-S-CD after birth are also consistent with our previous results on the p/p melanocytes. | |||||
| 書誌情報 |
Pigment Cell Research 巻 20, 号 3, p. 222-224, 発行日 2007-04 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0893-5785 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1111/j.1600-0749.2007.00370.x | |||||
