{"created":"2023-05-15T14:34:42.484328+00:00","id":44858,"links":{},"metadata":{"_buckets":{"deposit":"fb72e110-0d25-48fe-ad0b-726c37c894b3"},"_deposit":{"created_by":1,"id":"44858","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"44858"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00044858","sets":["1"]},"author_link":["445477","445474","445475","445476"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"224","bibliographicPageStart":"222","bibliographicVolumeNumber":"20","bibliographic_titles":[{"bibliographic_title":"Pigment Cell Research"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Pink-eyed dilution (p/p) mice produce greatly reduced (less than 1/10 that of black) levels of eumelanic pigment in follicular melanocytes in vivo. However, in the present study the plasma levels of 6H5MI2C and 5-S-CD in p/p mice at 7.5 days were 9-fold and 4-fold greater than in black mice. These results may appear surprising at first but are consistent with our finding that cultured p/p melanocytes fail to accumulate eumelanin and pheomelanin in the cells but release most of them (more than 90%) to the culture medium. The dramatic increases in the plasma levels of 6H5MI2C and 5-S-CD after birth are also consistent with our previous results on the p/p melanocytes.","subitem_description_type":"Abstract"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1111/j.1600-0749.2007.00370.x","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0893-5785","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Wakamatsu, Kazumasa"}],"nameIdentifiers":[{"nameIdentifier":"445474","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hirobe, Tomohisa"}],"nameIdentifiers":[{"nameIdentifier":"445475","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ito, Shosuke"}],"nameIdentifiers":[{"nameIdentifier":"445476","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"廣部 知久","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"445477","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"High levels of melanin-related metabolites in plasma from pink-eyed dilution mice","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"High levels of melanin-related metabolites in plasma from pink-eyed dilution mice"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2007-05-29"},"publish_date":"2007-05-29","publish_status":"0","recid":"44858","relation_version_is_last":true,"title":["High levels of melanin-related metabolites in plasma from pink-eyed dilution mice"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:10:31.025409+00:00"}