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In vivo measurement of acetylcholinesterase activity in the brain with a radioactive acetylcholine analog
https://repo.qst.go.jp/records/44448
https://repo.qst.go.jp/records/444487bbade91-3b87-45c5-9b32-c668db61d16d
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2006-07-07 | |||||
| タイトル | ||||||
| タイトル | In vivo measurement of acetylcholinesterase activity in the brain with a radioactive acetylcholine analog | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Namba, Hiroki
× Namba, Hiroki× Irie, Toshiaki× Fukushi, Kiyoshi× Iyo, Masaomi× 難波 宏樹× 入江 俊章× 福士 清 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | A novel method for visualization of brain acetylcholinesterase (AChE) in vivo has been developed. Following intravenous administration of radiolabelled acetylcholine analog, N-methyl-3-piperidyl acetate, there was very good agreement between the distribution of radioactivity and AChE activity in the brain of rat and monkey. The method would be applicable for in vivo studies of human brain AChE activity in disorders of central cholinergic systems such as Alzheimer's disease. | |||||
| 書誌情報 |
Brain Research 巻 667, p. 278-282, 発行日 1994 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0006-8993 | |||||
