@article{oai:repo.qst.go.jp:00044448, author = {Namba, Hiroki and Irie, Toshiaki and Fukushi, Kiyoshi and Iyo, Masaomi and 難波 宏樹 and 入江 俊章 and 福士 清}, journal = {Brain Research}, month = {}, note = {A novel method for visualization of brain acetylcholinesterase (AChE) in vivo has been developed. Following intravenous administration of radiolabelled acetylcholine analog, N-methyl-3-piperidyl acetate, there was very good agreement between the distribution of radioactivity and AChE activity in the brain of rat and monkey. The method would be applicable for in vivo studies of human brain AChE activity in disorders of central cholinergic systems such as Alzheimer's disease.}, pages = {278--282}, title = {In vivo measurement of acetylcholinesterase activity in the brain with a radioactive acetylcholine analog}, volume = {667}, year = {1994} }