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Enhancement of the relative uptake of 18F-FDG in mouse fibrosarcoma by rolipram
https://repo.qst.go.jp/records/44389
https://repo.qst.go.jp/records/44389039f6587-3df7-4fae-86f9-23fe8048a740
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2006-07-03 | |||||
タイトル | ||||||
タイトル | Enhancement of the relative uptake of 18F-FDG in mouse fibrosarcoma by rolipram | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Kobayashi, Kaoru
× Kobayashi, Kaoru× Hosoi, Rie× Momosaki, Sotaro× Koike, Sachiko× Ando, Koichi× Nishimura, Tsunehiko× Inoue, Osamu× 細井 理恵× 小池 幸子× 安藤 興一× 井上 修 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | fluorodeoxyglucose(18F-FDG) in tumor tissue was examined in mice transplanted with FNSa firbrosarcoma. The uptake indexes of 18F-FDG in the heart, skeletal muscle and brain remarkably decreased after treatment with 3 mg/kg of roliprom (heart:13%, skeletal muscle:14%, brain :13%), but fibrosarcoma tissue showed only a 50% reduction in the uptake of 18F-FDG. The tumor/muscle ratio of radioactivity 30 min after 18F-FDG injection was consequently enhanced from 1.9 to 6.5 by roliprom. This indicates the possible use of roliprom to enhance the sensitivity of tumor detection, as well as characterization of tumors in 18F-FDG PET. | |||||
書誌情報 |
Annals of Nuclear Medicine 巻 16, p. 507-510, 発行日 2002 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0914-7187 |