WEKO3
アイテム
Sensitive measurement of positron emitters eluted from HPLC
https://repo.qst.go.jp/records/44306
https://repo.qst.go.jp/records/44306816fbf20-7c81-4e60-9009-e22fdbbc5ba0
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2006-06-21 | |||||
| タイトル | ||||||
| タイトル | Sensitive measurement of positron emitters eluted from HPLC | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Takei, Makoto
× Takei, Makoto× Kida, Takayo× Suzuki, Kazutoshi× 鈴木 和年 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | For sensitive analysis of the radioactive-metabolite in human PET, a radio-HPLC system coupled to a newly designed positron detector was constructed. The detector had the advantages of low noise level(1.7+/-1.0cpm)and high sensitivity(32+/-1%)due to coincidence counting and large BGO crystals. Furthermore, the detector was easy to move,since a pair of the BGO housings coupled to photomultipliers was effectively arranged in parallel and a HPLC cell with different volume could be inserted between the BGO housing. This radio-HPLC system was useful for analyzing samples with low radioactivity. It was applied to the measurement of [11C]FLB457in plasma,having high affinity and high selectivity with dopamine D2 receptors. Extremely low radioactivity of [11C]FLB457(2500dpm)could be analzed by using the radio-HPLC system. The performance of this detector was compared with those of commercially available systems that had been used as sensitive detectors for HPLC. (C)2001 Elsevier Science Ltd. All rights reserved. | |||||
| 書誌情報 |
Applied Radiation and Isotopes 巻 55, p. 229-234, 発行日 2001 |
|||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0969-8043 | |||||
