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Outcomes of visual acuity in carbon ion radiotherapy:analysis of dose-volume histograms and prognostic factors
https://repo.qst.go.jp/records/43998
https://repo.qst.go.jp/records/439981f8c9ffd-488e-428d-bbc4-50c7b760a36d
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2006-03-15 | |||||
タイトル | ||||||
タイトル | Outcomes of visual acuity in carbon ion radiotherapy:analysis of dose-volume histograms and prognostic factors | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Hasegawa, Azusa
× Hasegawa, Azusa× Mizoe, Junetsu× Mizota, Atsushi× Tsujii, Hirohiko× 長谷川 安都佐× 溝江 純悦× 溝田 淳× 辻井 博彦 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The Heavy Ion Medical Accelerator in Chiba (HIMAC) has been operting since 1993 at the National Institute of Radiological Sciences as the first clinical heavy in the world (1). From June 1994 to February 2005, 2,192 patients with various types of tumors were enrolled into clinical trials using carbon ion beams generated by the HIMAC. Tsujii et al. (2,3) reported the preliminary results of carbon ion radiotherapy, including radiation-induced morbidity, local control, and survial rates for patients treated for tumors in multiple sites. Because of its increased biologic potential for the destruction of radioresistant tumors and its improved dose localization properties, carbon ion radiotheapy has also been applied to the treatment of head-and-neck tumors. In radiotherapy of head-and -neck tumors, the preservation of visual acuity is of paramount for both patient and treating physician. Several studies have analyzed the tolerance dose of the optic nerve (ON) and chiasm to photon or proton bea radiotherapy (4-7). Although carbon ions have a superior dose distribution as compared with potons, in particular, it is difficult to protect the adjacent tissues when the tumors are located close to or involved in critical organs. In this article, we have evaluated the dose-complication probability for the impairment or retention of visual in carbon ion radiotherapy, using dose-volume histograms (DVHs). |
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書誌情報 |
International Journal of Radiation Oncology Biology Physics 巻 64, 号 2, p. 396-401, 発行日 2006-02 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0360-3016 |