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Carbon -11-methionine positron emission tomography imaging of chordoma
https://repo.qst.go.jp/records/43603
https://repo.qst.go.jp/records/43603b0ff3b9f-a7de-48c4-9afd-f1716fe6a402
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2005-01-07 | |||||
| タイトル | ||||||
| タイトル | Carbon -11-methionine positron emission tomography imaging of chordoma | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Zhang, Hong
× Zhang, Hong× Yoshikawa, Kyosan× Tamura, Katsumi× Sagou, Kenji× Mei, Tian× Suhara, Tetsuya× Kandatsu, Susumu× Suzuki, Kazutoshi× Tanada, Shuji× Tsujii, Hirohiko× 張 宏× 吉川 京燦× 田村 克巳× 佐合 賢治× 須原 哲也× 神立 進× 鈴木 和年× 棚田 修二× 辻井 博彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Objective Chordoma is a rare malignant bone tumor that arises from notochord remnants. This is the first trial to investigate the utility of 11C-methionine(MET) positron emission tomography(PET) in the imaging of chordoma before and after carbon-ion radiotherapy(CIRT). Design and patients Fifteen patients with chordoma were investigated with MET-PET before and after CIRT and the findings analyzed visually and quantitatively. Tumor MET uptake was evaluated by tumor-to-nontumor ratio(T/N ratio). Results In 12(80%) patients chordoma was clearly visible in the baseline MET-PET study with a mean T/N ratio of 3.3±1.7. The MET uptake decreased significantly to 2.3±1.4 after CIRT(P＜0.05). A significant reduction in tumor MET uptake of 24% was observed after CIRT. Fourteen (93%) patients showed no local recurrence after CIRT with a median follow-up time of 20 months. Conclusion This study has demonstrated that MET-PET is feasible for imaging of chordoma. MET-PET could provide important tumor metabolic information for the therapeutic monitoring of chordoma after CIRT. |
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| 書誌情報 |
Skeletal Radiology 巻 33, 号 9, p. 524-530, 発行日 2004-09 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0364-2348 | |||||
