WEKO3
アイテム
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This is the first trial to investigate the utility of 11C-methionine(MET) positron emission tomography(PET) in the imaging of chordoma before and after carbon-ion radiotherapy(CIRT).\nDesign and patients Fifteen patients with chordoma were investigated with MET-PET before and after CIRT and the findings analyzed visually and quantitatively. Tumor MET uptake was evaluated by tumor-to-nontumor ratio(T/N ratio).\nResults In 12(80%) patients chordoma was clearly visible in the baseline MET-PET study with a mean T/N ratio of 3.3±1.7. The MET uptake decreased significantly to 2.3±1.4 after CIRT(P<0.05). A significant reduction in tumor MET uptake of 24% was observed after CIRT. Fourteen (93%) patients showed no local recurrence after CIRT with a median follow-up time of 20 months.\nConclusion This study has demonstrated that MET-PET is feasible for imaging of chordoma. MET-PET could provide important tumor metabolic information for the therapeutic monitoring of chordoma after CIRT.", "subitem_description_type": "Abstract"}]}, "item_8_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0364-2348", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Zhang, Hong"}], "nameIdentifiers": [{"nameIdentifier": "433522", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshikawa, Kyosan"}], "nameIdentifiers": [{"nameIdentifier": "433523", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tamura, Katsumi"}], "nameIdentifiers": [{"nameIdentifier": "433524", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sagou, Kenji"}], "nameIdentifiers": [{"nameIdentifier": "433525", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mei, Tian"}], "nameIdentifiers": [{"nameIdentifier": "433526", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suhara, Tetsuya"}], "nameIdentifiers": [{"nameIdentifier": "433527", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kandatsu, Susumu"}], "nameIdentifiers": [{"nameIdentifier": "433528", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suzuki, Kazutoshi"}], "nameIdentifiers": [{"nameIdentifier": "433529", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanada, Shuji"}], "nameIdentifiers": [{"nameIdentifier": "433530", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tsujii, Hirohiko"}], "nameIdentifiers": [{"nameIdentifier": "433531", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "張 宏", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "433532", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "吉川 京燦", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "433533", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "田村 克巳", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "433534", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "佐合 賢治", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "433535", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "須原 哲也", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "433536", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "神立 進", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "433537", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "鈴木 和年", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "433538", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "棚田 修二", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "433539", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "辻井 博彦", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "433540", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Carbon -11-methionine positron emission tomography imaging of chordoma", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Carbon -11-methionine positron emission tomography imaging of chordoma"}]}, "item_type_id": "8", "owner": "1", "path": ["1"], "permalink_uri": "https://repo.qst.go.jp/records/43603", "pubdate": {"attribute_name": "公開日", "attribute_value": "2005-01-07"}, "publish_date": "2005-01-07", "publish_status": "0", "recid": "43603", "relation": {}, "relation_version_is_last": true, "title": ["Carbon -11-methionine positron emission tomography imaging of chordoma"], "weko_shared_id": -1}
Carbon -11-methionine positron emission tomography imaging of chordoma
https://repo.qst.go.jp/records/43603
https://repo.qst.go.jp/records/43603b0ff3b9f-a7de-48c4-9afd-f1716fe6a402
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2005-01-07 | |||||
タイトル | ||||||
タイトル | Carbon -11-methionine positron emission tomography imaging of chordoma | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Zhang, Hong
× Zhang, Hong× Yoshikawa, Kyosan× Tamura, Katsumi× Sagou, Kenji× Mei, Tian× Suhara, Tetsuya× Kandatsu, Susumu× Suzuki, Kazutoshi× Tanada, Shuji× Tsujii, Hirohiko× 張 宏× 吉川 京燦× 田村 克巳× 佐合 賢治× 須原 哲也× 神立 進× 鈴木 和年× 棚田 修二× 辻井 博彦 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objective Chordoma is a rare malignant bone tumor that arises from notochord remnants. This is the first trial to investigate the utility of 11C-methionine(MET) positron emission tomography(PET) in the imaging of chordoma before and after carbon-ion radiotherapy(CIRT). Design and patients Fifteen patients with chordoma were investigated with MET-PET before and after CIRT and the findings analyzed visually and quantitatively. Tumor MET uptake was evaluated by tumor-to-nontumor ratio(T/N ratio). Results In 12(80%) patients chordoma was clearly visible in the baseline MET-PET study with a mean T/N ratio of 3.3±1.7. The MET uptake decreased significantly to 2.3±1.4 after CIRT(P<0.05). A significant reduction in tumor MET uptake of 24% was observed after CIRT. Fourteen (93%) patients showed no local recurrence after CIRT with a median follow-up time of 20 months. Conclusion This study has demonstrated that MET-PET is feasible for imaging of chordoma. MET-PET could provide important tumor metabolic information for the therapeutic monitoring of chordoma after CIRT. |
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書誌情報 |
Skeletal Radiology 巻 33, 号 9, p. 524-530, 発行日 2004-09 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0364-2348 |