{"created":"2023-05-15T14:33:36.897218+00:00","id":43603,"links":{},"metadata":{"_buckets":{"deposit":"99cbaa9b-5428-42ae-93c3-4ad881d540c2"},"_deposit":{"created_by":1,"id":"43603","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"43603"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00043603","sets":["1"]},"author_link":["433540","433527","433530","433532","433533","433528","433536","433523","433524","433526","433538","433537","433529","433531","433534","433539","433535","433522","433525"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"9","bibliographicPageEnd":"530","bibliographicPageStart":"524","bibliographicVolumeNumber":"33","bibliographic_titles":[{"bibliographic_title":"Skeletal Radiology"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective Chordoma is a rare malignant bone tumor that arises from notochord remnants. This is the first trial to investigate the utility of 11C-methionine(MET) positron emission tomography(PET) in the imaging of chordoma before and after carbon-ion radiotherapy(CIRT).\nDesign and patients Fifteen patients with chordoma were investigated with MET-PET before and after CIRT and the findings analyzed visually and quantitatively. Tumor MET uptake was evaluated by tumor-to-nontumor ratio(T/N ratio).\nResults In 12(80%) patients chordoma was clearly visible in the baseline MET-PET study with a mean T/N ratio of 3.3±1.7. The MET uptake decreased significantly to 2.3±1.4 after CIRT(P＜0.05). A significant reduction in tumor MET uptake of 24% was observed after CIRT. Fourteen (93%) patients showed no local recurrence after CIRT with a median follow-up time of 20 months.\nConclusion This study has demonstrated that MET-PET is feasible for imaging of chordoma. MET-PET could provide important tumor metabolic information for the therapeutic monitoring of chordoma after CIRT.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0364-2348","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Zhang, Hong"}],"nameIdentifiers":[{"nameIdentifier":"433522","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshikawa, Kyosan"}],"nameIdentifiers":[{"nameIdentifier":"433523","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tamura, Katsumi"}],"nameIdentifiers":[{"nameIdentifier":"433524","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sagou, Kenji"}],"nameIdentifiers":[{"nameIdentifier":"433525","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mei, Tian"}],"nameIdentifiers":[{"nameIdentifier":"433526","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suhara, Tetsuya"}],"nameIdentifiers":[{"nameIdentifier":"433527","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kandatsu, Susumu"}],"nameIdentifiers":[{"nameIdentifier":"433528","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Kazutoshi"}],"nameIdentifiers":[{"nameIdentifier":"433529","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanada, Shuji"}],"nameIdentifiers":[{"nameIdentifier":"433530","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsujii, Hirohiko"}],"nameIdentifiers":[{"nameIdentifier":"433531","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"張 宏","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433532","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"吉川 京燦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433533","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田村 克巳","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433534","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐合 賢治","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433535","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須原 哲也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433536","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"神立 進","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433537","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木 和年","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433538","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"棚田 修二","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433539","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻井 博彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433540","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Carbon -11-methionine positron emission tomography imaging of chordoma","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Carbon -11-methionine positron emission tomography imaging of chordoma"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2005-01-07"},"publish_date":"2005-01-07","publish_status":"0","recid":"43603","relation_version_is_last":true,"title":["Carbon -11-methionine positron emission tomography imaging of chordoma"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:25:15.890961+00:00"}