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Washout measurement of radioisotope implanted by radioactive beams in the rabbit
https://repo.qst.go.jp/records/43316
https://repo.qst.go.jp/records/43316fac1cc94-a162-44ae-8c7c-60e94fb45401
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2004-01-06 | |||||
| タイトル | ||||||
| タイトル | Washout measurement of radioisotope implanted by radioactive beams in the rabbit | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Mizuno, Hideyuki
× Mizuno, Hideyuki× Tomitani, Takehiro× Kanazawa, Mitsutaka× Kitagawa, Atsushi× Pawelke, Jorg× Iseki, Yasushi× Urakabe, Eriko× Suda, Mitsuru× Kawano, Akihiro× Iritani, Riichirou× Matsushita, Satoru× Inaniwa, Taku× Nishio, Teiji× Furukawa, Shigeo× Ando, Koichi× Nakamura, Yuzuru× Kanai, Tatsuaki× 水野 秀之× 富谷 武浩× 金澤 光隆× 北川 敦志× Ｊｏｒｇ Ｐａｗｅｌｋｅ× 井関 康× 新谷 恵理子× 須田 充× 河野 明広× 入谷 理一郎× 松下 悟× 稲庭 拓× 西尾 禎治× 古川 重夫× 安藤 興一× 中村 譲× 金井 達明 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Washout of 10C and 11C implanted by radioactive beams in brain and thigh muscle of rabbits was studied. The biological washout effect in living body is important in the range verification system or three-dimensional volume imaging in heavy ion therapy. Positron emitter beams were implanted in the rabbit and the annihilation gamma-rays were measured by in situ positron camera which consisted of a pair of scintillation cameras set on either side of the target. The ROI (region of interest) was set as a two-dimensional position distribution and the time-activity curve of the ROI was measured. Experiments were done under two conditions: live and dead. By comparing the two sets of measurement data, it was deduced that there are at least three components in the washout process. Time-activity curves of both brain and thigh muscle were clearly explained by the three-component model analysis. The three components ratios (and wash out half-lives) were 35 % (2.0 s), 30 % (140 s) and 35 % (10191 s) for brain and 30 % (10 s), 19 % (195 s) and 52 % (3175 s) for thigh muscle. The washout effect must be taken into account for the verification of treatment plans by means of positron camera measurements. | |||||
| 書誌情報 |
Physics in Medicine and Biology 巻 48, p. 2269-2281, 発行日 2003-07 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0031-9155 | |||||
