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Functional characterization of the human spermidine / spermine N1 - acetyltransferase gene promoter
https://repo.qst.go.jp/records/43267
https://repo.qst.go.jp/records/43267f1055c06-b511-40e5-a5ec-c14dd7da5df4
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2003-11-14 | |||||
| タイトル | ||||||
| タイトル | Functional characterization of the human spermidine / spermine N1 - acetyltransferase gene promoter | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Tomitori, Hideyuki
× Tomitori, Hideyuki× Nenoi, Mitsuru× Mita, Kazuei× Daino, Kazuhiro× Igarashi, Kazuei× Ichimura, Sachiko× 根井 充× 三田 和英× 臺野 和広× 沼田 幸子 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Spermidine / spermine N1-acetyltransferase (SSAT), the key enzyme of polyamine catabolism, is induced by antiproliferative stresses. We analyzed the 5'flanking region of the human SSAT gene, and clarified that the binding of Spl to the GC-box located 42 to 51 bp upstream from the transcription start site is essential for transcription in Hela S3 cells. A polyamine-responsive element (PRE) seemed to be responsible for the elevated transcription after X-ray irradiation. | |||||
| 書誌情報 |
Biochimica et Biophysica Acta. General Subjects 巻 1579, p. 180-184, 発行日 2002 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0304-4165 | |||||
