@article{oai:repo.qst.go.jp:00043267, author = {Tomitori, Hideyuki and Nenoi, Mitsuru and Mita, Kazuei and Daino, Kazuhiro and Igarashi, Kazuei and Ichimura, Sachiko and 根井 充 and 三田 和英 and 臺野 和広 and 沼田 幸子}, journal = {Biochimica et Biophysica Acta. General Subjects}, month = {}, note = {Spermidine / spermine N1-acetyltransferase (SSAT), the key enzyme of polyamine catabolism, is induced by antiproliferative stresses. We analyzed the 5'flanking region of the human SSAT gene, and clarified that the binding of Spl to the GC-box located 42 to 51 bp upstream from the transcription start site is essential for transcription in Hela S3 cells. A polyamine-responsive element (PRE) seemed to be responsible for the elevated transcription after X-ray irradiation.}, pages = {180--184}, title = {Functional characterization of the human spermidine / spermine N1 - acetyltransferase gene promoter}, volume = {1579}, year = {2002} }