WEKO3
アイテム
{"_buckets": {"deposit": "7143bb2f-2d77-4705-bcf0-41733d69e132"}, "_deposit": {"created_by": 1, "id": "71230", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "71230"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00071230", "sets": ["28"]}, "author_link": ["700161", "700165", "700164", "700167", "700163", "700162", "700168", "700166"], "item_10005_date_7": {"attribute_name": "発表年月日", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2007-06-06", "subitem_date_issued_type": "Issued"}]}, "item_10005_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Objectives: The purpose of this study was to evaluate the effects of hyperglycemia on FDG uptake of the brain, liver, muscle and tumor in clinical situation.\nMethods: Fifty-seven patients (mean age: 64.8+-8.9, range: 42-79, male : female=40 : 17) who showed blood glucose level more than 200 mg/dl at the time of examination (mean glucose level: 255.5+-69.3, range: 201-666) were included in this retrospective study. All patients received FDG-PET scan for suspected cancer in Kyoto University Hospital from January 2001 to December 2005 and fasted at least 4 hours before PET study. Reasons of hyperglycemia were follows; untreated diabetes: n=5, uncontrolled diabetes: n=32, unknown: n=20. FDG accumulation of the tumor was visually analyzed. SUV of the brain, liver, muscle and tumor were also analyzed.\nResults: Presence or absence of malignant lesion was confirmed by other modality such as CT, surgery, and clinical follow-up at least 6 month in 49 patients and malignant lesion(s) were finally diagnosed in 35 patients. Twenty eight of 35 patients had positive results by visual analysis (lung cancer: 7, pancreas cancer: 7, liver metastases: 3, lung metastases: 3, hepatocellular carcinoma: 2, bone metastases: 2, etc.) and the average of tumor SUV was 5.7+-2.5. False negative results were observed in 7 cases which consisted of so-called low-FDG-avid tumors (hepatocellular carcinoma: 3, pancreas cancer: 3, small lung metastasis from pancreas cancer: 1) and the average of tumor SUV was 2.7+-0.8. In contrast to relatively stable tumor FDG uptake, brain FDG uptake tended to be lower in this high glucose level (SUV=4.4+-1.1), as compared to that in normoglycemia (SUV=11.8+-2.6). Liver, muscle and tumor FDG uptake didnt show clear correlation with blood glucose level. Specificity, sensitivity and PPV of FDG-PET scan were 67%, 97% and 80% respectively. \nConclusions: In spite of high blood glucose level (more than 200 mg/dl),\nFDG uptake of the tumor maintained enough high level for visual diagnosis in majority of cases, except for the cases of low-FDG-avid tumors, such as hepatocellular carcinoma and pancreas cancer.", "subitem_description_type": "Abstract"}]}, "item_10005_description_6": {"attribute_name": "会議概要(会議名, 開催地, 会期, 主催者等)", "attribute_value_mlt": [{"subitem_description": "Society of nuclear medicine 54rd Annual Meetng", "subitem_description_type": "Other"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Hara, Tadashi"}], "nameIdentifiers": [{"nameIdentifier": "700161", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Higashi, Tatsuya"}], "nameIdentifiers": [{"nameIdentifier": "700162", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishizu, Koichi"}], "nameIdentifiers": [{"nameIdentifier": "700163", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suga, Tsuyoshi"}], "nameIdentifiers": [{"nameIdentifier": "700164", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakamoto, Yuji"}], "nameIdentifiers": [{"nameIdentifier": "700165", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Saga, Tsuneo"}], "nameIdentifiers": [{"nameIdentifier": "700166", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Togashi, Kaori"}], "nameIdentifiers": [{"nameIdentifier": "700167", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "佐賀 恒夫", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "700168", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "conference object", "resourceuri": "http://purl.org/coar/resource_type/c_c94f"}]}, "item_title": "Clinical effects of hyperglycemia on FDG uptake of tumor and brain in patients with suspected cancer.", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Clinical effects of hyperglycemia on FDG uptake of tumor and brain in patients with suspected cancer."}]}, "item_type_id": "10005", "owner": "1", "path": ["28"], "permalink_uri": "https://repo.qst.go.jp/records/71230", "pubdate": {"attribute_name": "公開日", "attribute_value": "2013-09-03"}, "publish_date": "2013-09-03", "publish_status": "0", "recid": "71230", "relation": {}, "relation_version_is_last": true, "title": ["Clinical effects of hyperglycemia on FDG uptake of tumor and brain in patients with suspected cancer."], "weko_shared_id": -1}
Clinical effects of hyperglycemia on FDG uptake of tumor and brain in patients with suspected cancer.
https://repo.qst.go.jp/records/71230
https://repo.qst.go.jp/records/71230b8df2616-40eb-448c-8933-8d25f4a47121
Item type | 会議発表用資料 / Presentation(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2013-09-03 | |||||
タイトル | ||||||
タイトル | Clinical effects of hyperglycemia on FDG uptake of tumor and brain in patients with suspected cancer. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
資源タイプ | conference object | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Hara, Tadashi
× Hara, Tadashi× Higashi, Tatsuya× Ishizu, Koichi× Suga, Tsuyoshi× Nakamoto, Yuji× Saga, Tsuneo× Togashi, Kaori× 佐賀 恒夫 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objectives: The purpose of this study was to evaluate the effects of hyperglycemia on FDG uptake of the brain, liver, muscle and tumor in clinical situation. Methods: Fifty-seven patients (mean age: 64.8+-8.9, range: 42-79, male : female=40 : 17) who showed blood glucose level more than 200 mg/dl at the time of examination (mean glucose level: 255.5+-69.3, range: 201-666) were included in this retrospective study. All patients received FDG-PET scan for suspected cancer in Kyoto University Hospital from January 2001 to December 2005 and fasted at least 4 hours before PET study. Reasons of hyperglycemia were follows; untreated diabetes: n=5, uncontrolled diabetes: n=32, unknown: n=20. FDG accumulation of the tumor was visually analyzed. SUV of the brain, liver, muscle and tumor were also analyzed. Results: Presence or absence of malignant lesion was confirmed by other modality such as CT, surgery, and clinical follow-up at least 6 month in 49 patients and malignant lesion(s) were finally diagnosed in 35 patients. Twenty eight of 35 patients had positive results by visual analysis (lung cancer: 7, pancreas cancer: 7, liver metastases: 3, lung metastases: 3, hepatocellular carcinoma: 2, bone metastases: 2, etc.) and the average of tumor SUV was 5.7+-2.5. False negative results were observed in 7 cases which consisted of so-called low-FDG-avid tumors (hepatocellular carcinoma: 3, pancreas cancer: 3, small lung metastasis from pancreas cancer: 1) and the average of tumor SUV was 2.7+-0.8. In contrast to relatively stable tumor FDG uptake, brain FDG uptake tended to be lower in this high glucose level (SUV=4.4+-1.1), as compared to that in normoglycemia (SUV=11.8+-2.6). Liver, muscle and tumor FDG uptake didnt show clear correlation with blood glucose level. Specificity, sensitivity and PPV of FDG-PET scan were 67%, 97% and 80% respectively. Conclusions: In spite of high blood glucose level (more than 200 mg/dl), FDG uptake of the tumor maintained enough high level for visual diagnosis in majority of cases, except for the cases of low-FDG-avid tumors, such as hepatocellular carcinoma and pancreas cancer. |
|||||
会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Society of nuclear medicine 54rd Annual Meetng | |||||
発表年月日 | ||||||
日付 | 2007-06-06 | |||||
日付タイプ | Issued |