{"created":"2023-05-15T14:52:08.971124+00:00","id":71230,"links":{},"metadata":{"_buckets":{"deposit":"7143bb2f-2d77-4705-bcf0-41733d69e132"},"_deposit":{"created_by":1,"id":"71230","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"71230"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00071230","sets":["10:28"]},"author_link":["700161","700165","700164","700167","700163","700162","700168","700166"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2007-06-06","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objectives: The purpose of this study was to evaluate the effects of hyperglycemia on FDG uptake of the brain, liver, muscle and tumor in clinical situation.\nMethods: Fifty-seven patients (mean age: 64.8+-8.9, range: 42-79, male : female=40 : 17) who showed blood glucose level more than 200 mg/dl at the time of examination (mean glucose level: 255.5+-69.3, range: 201-666) were included in this retrospective study. All patients received FDG-PET scan for suspected cancer in Kyoto University Hospital from January 2001 to December 2005 and fasted at least 4 hours before PET study.  Reasons of hyperglycemia were follows; untreated diabetes: n=5, uncontrolled diabetes: n=32, unknown: n=20. FDG accumulation of the tumor was visually analyzed. SUV of the brain, liver, muscle and tumor were also analyzed.\nResults: Presence or absence of malignant lesion was confirmed by other modality such as CT, surgery, and clinical follow-up at least 6 month in 49 patients and malignant lesion(s) were finally diagnosed in 35 patients. Twenty eight of 35 patients had positive results by visual analysis (lung cancer: 7, pancreas cancer: 7, liver metastases: 3, lung metastases: 3, hepatocellular carcinoma: 2, bone metastases: 2, etc.) and the average of tumor SUV was 5.7+-2.5. False negative results were observed in 7 cases which consisted of so-called low-FDG-avid tumors (hepatocellular carcinoma: 3, pancreas cancer: 3, small lung metastasis from pancreas cancer: 1) and the average of tumor SUV was 2.7+-0.8. In contrast to relatively stable tumor FDG uptake, brain FDG uptake tended to be lower in this high glucose level (SUV=4.4+-1.1), as compared to that in normoglycemia (SUV=11.8+-2.6). Liver, muscle and tumor FDG uptake didnt show clear correlation with blood glucose level. Specificity, sensitivity and PPV of FDG-PET scan were 67%, 97% and 80% respectively. \nConclusions: In spite of high blood glucose level (more than 200 mg/dl),\nFDG uptake of the tumor maintained enough high level for visual diagnosis in majority of cases, except for the cases of low-FDG-avid tumors, such as hepatocellular carcinoma and pancreas cancer.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"Society of nuclear medicine 54rd Annual Meetng","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hara, Tadashi"}],"nameIdentifiers":[{"nameIdentifier":"700161","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Higashi, Tatsuya"}],"nameIdentifiers":[{"nameIdentifier":"700162","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishizu, Koichi"}],"nameIdentifiers":[{"nameIdentifier":"700163","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suga, Tsuyoshi"}],"nameIdentifiers":[{"nameIdentifier":"700164","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakamoto, Yuji"}],"nameIdentifiers":[{"nameIdentifier":"700165","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Saga, Tsuneo"}],"nameIdentifiers":[{"nameIdentifier":"700166","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Togashi, Kaori"}],"nameIdentifiers":[{"nameIdentifier":"700167","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐賀 恒夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"700168","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Clinical effects of hyperglycemia on FDG uptake of tumor and brain in patients with suspected cancer.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Clinical effects of hyperglycemia on FDG uptake of tumor and brain in patients with suspected cancer."}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-09-03"},"publish_date":"2013-09-03","publish_status":"0","recid":"71230","relation_version_is_last":true,"title":["Clinical effects of hyperglycemia on FDG uptake of tumor and brain in patients with suspected cancer."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T19:53:39.936100+00:00"}