WEKO3
アイテム
{"_buckets": {"deposit": "381af3fd-f6d2-481e-a2c3-5ddc4aa9f9ed"}, "_deposit": {"created_by": 1, "id": "69659", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "69659"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00069659", "sets": ["28"]}, "author_link": ["683790", "683791", "683796", "683786", "683800", "683797", "683788", "683787", "683789", "683785", "683794", "683798", "683792", "683793", "683799", "683795", "683784"], "item_10005_date_7": {"attribute_name": "発表年月日", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2008-10-30", "subitem_date_issued_type": "Issued"}]}, "item_10005_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Background and Purpose: Carbon-ion radiotherapy (C-ion RT) for non-small cell lung cancer (NSCLC) is a low invasive therapy with good local control. But in less than 10% of all cases in-field local recurrence is ascertained. Additionally, grade 2 adverse reactions in lung or skin were observed in patients less than 5%. Because early assessment of these radioresistance and toxicity is valuable in C-ion RT, non-invasive and accurate biomarkers are required. Using peptidomic approach for serum samples from NSCLC patients, we aimed to discover biomarkers useful for monitoring responses of tumor and normal tissue after C-ion RT. \nMaterial and Method: We enrolled 30 NSCLC patients who underwent C-ion RT in our hospital from September, 2006 to August, 2007. Serum samples were collected from these patients before treatment and 1 day and 1, 3, 6 months after treatment. Then we prepared 5muL of serum with magnetic beads and profiled serum peptidome using MALDI-TOF MS( Bruker Daltonics Inc.).\nResult: Some peaks showed significant changes before and after treatment. Conclusion: These peaks have potentials to be novel biomarkers for monitoring therapeutic response or toxicity.", "subitem_description_type": "Abstract"}]}, "item_10005_description_6": {"attribute_name": "会議概要(会議名, 開催地, 会期, 主催者等)", "attribute_value_mlt": [{"subitem_description": "第67回日本癌学会学術総会", "subitem_description_type": "Other"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "中嶋, 美緒"}], "nameIdentifiers": [{"nameIdentifier": "683784", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "梅村, 啓史"}], "nameIdentifiers": [{"nameIdentifier": "683785", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "馬場, 雅行"}], "nameIdentifiers": [{"nameIdentifier": "683786", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "須金, 紀雄"}], "nameIdentifiers": [{"nameIdentifier": "683787", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "山本, 直敬"}], "nameIdentifiers": [{"nameIdentifier": "683788", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "鎌田, 正"}], "nameIdentifiers": [{"nameIdentifier": "683789", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "溝江, 純悦"}], "nameIdentifiers": [{"nameIdentifier": "683790", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "辻井, 博彦"}], "nameIdentifiers": [{"nameIdentifier": "683791", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "朝長, 毅"}], "nameIdentifiers": [{"nameIdentifier": "683792", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "野村, 文夫"}], "nameIdentifiers": [{"nameIdentifier": "683793", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "中嶋 美緒", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "683794", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "馬場 雅行", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "683795", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "須金 紀雄", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "683796", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "山本 直敬", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "683797", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "鎌田 正", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "683798", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "溝江 純悦", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "683799", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "辻井 博彦", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "683800", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "conference object", "resourceuri": "http://purl.org/coar/resource_type/c_c94f"}]}, "item_title": "非小細胞肺癌症例における炭素イオン線治療前後の血清ペプチドーム解析", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "非小細胞肺癌症例における炭素イオン線治療前後の血清ペプチドーム解析"}]}, "item_type_id": "10005", "owner": "1", "path": ["28"], "permalink_uri": "https://repo.qst.go.jp/records/69659", "pubdate": {"attribute_name": "公開日", "attribute_value": "2008-12-19"}, "publish_date": "2008-12-19", "publish_status": "0", "recid": "69659", "relation": {}, "relation_version_is_last": true, "title": ["非小細胞肺癌症例における炭素イオン線治療前後の血清ペプチドーム解析"], "weko_shared_id": -1}
非小細胞肺癌症例における炭素イオン線治療前後の血清ペプチドーム解析
https://repo.qst.go.jp/records/69659
https://repo.qst.go.jp/records/696593ea7b2aa-9048-41b6-baaa-20ff1ddd2c2c
Item type | 会議発表用資料 / Presentation(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2008-12-19 | |||||
タイトル | ||||||
タイトル | 非小細胞肺癌症例における炭素イオン線治療前後の血清ペプチドーム解析 | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
資源タイプ | conference object | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
中嶋, 美緒
× 中嶋, 美緒× 梅村, 啓史× 馬場, 雅行× 須金, 紀雄× 山本, 直敬× 鎌田, 正× 溝江, 純悦× 辻井, 博彦× 朝長, 毅× 野村, 文夫× 中嶋 美緒× 馬場 雅行× 須金 紀雄× 山本 直敬× 鎌田 正× 溝江 純悦× 辻井 博彦 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background and Purpose: Carbon-ion radiotherapy (C-ion RT) for non-small cell lung cancer (NSCLC) is a low invasive therapy with good local control. But in less than 10% of all cases in-field local recurrence is ascertained. Additionally, grade 2 adverse reactions in lung or skin were observed in patients less than 5%. Because early assessment of these radioresistance and toxicity is valuable in C-ion RT, non-invasive and accurate biomarkers are required. Using peptidomic approach for serum samples from NSCLC patients, we aimed to discover biomarkers useful for monitoring responses of tumor and normal tissue after C-ion RT. Material and Method: We enrolled 30 NSCLC patients who underwent C-ion RT in our hospital from September, 2006 to August, 2007. Serum samples were collected from these patients before treatment and 1 day and 1, 3, 6 months after treatment. Then we prepared 5muL of serum with magnetic beads and profiled serum peptidome using MALDI-TOF MS( Bruker Daltonics Inc.). Result: Some peaks showed significant changes before and after treatment. Conclusion: These peaks have potentials to be novel biomarkers for monitoring therapeutic response or toxicity. |
|||||
会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 第67回日本癌学会学術総会 | |||||
発表年月日 | ||||||
日付 | 2008-10-30 | |||||
日付タイプ | Issued |