WEKO3
アイテム
{"_buckets": {"deposit": "d8d6382a-2faa-43af-a1bc-aa0d0977a13c"}, "_deposit": {"created_by": 1, "id": "47672", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "47672"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00047672", "sets": ["1"]}, "author_link": ["478301", "478298", "478302", "478297", "478303", "478304", "478299", "478300"], "item_8_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2012-08", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "10", "bibliographicPageEnd": "386", "bibliographicPageStart": "383", "bibliographicVolumeNumber": "55", "bibliographic_titles": [{"bibliographic_title": "Journal of Labelled Compounds \u0026 Radiopharmaceuticals"}]}]}, "item_8_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "We report a novel labeling method for the rapid radiochlorination of aromatic compounds using no-carrier-added short half-life radioactive chloride ions ([38,39Cl]Cl-and [34mCl]Cl-) and OXONE (Sigma-Aldrich, Japan) as an oxidation reagent.The reaction of radioactive chloride ions with anisole in the presence of OXONE gave a mixture of p-[*Cl]chloroanisole and o-[*Cl]-chloroanisole, with a radiochemical conversion yield ofmore than 85%(not decay corrected) and selectivity of 7:3,within 10 min. Regioselective radioactive chlorination was achieved by chlorodestannylation of tributylstannyl compounds to afford the corresponding radiochlorinated compounds (p-chloroanisole and m-chloroanisole) in satisfactory radiochemical yields (80\u0026#8211;95% and 46\u0026#8211;65%, respectively).", "subitem_description_type": "Abstract"}]}, "item_8_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1002/jlcr.2957", "subitem_relation_type_select": "DOI"}}]}, "item_8_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0362-4803", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Takada, Yuuki"}], "nameIdentifiers": [{"nameIdentifier": "478297", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hanyu, Masayuki"}], "nameIdentifiers": [{"nameIdentifier": "478298", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagatsu, Koutarou"}], "nameIdentifiers": [{"nameIdentifier": "478299", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Fukumura, Toshimitsu"}], "nameIdentifiers": [{"nameIdentifier": "478300", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "高田 由貴", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "478301", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "破入 正行", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "478302", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "永津 弘太郎", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "478303", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "福村 利光", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "478304", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Radiolabeling of aromatic compounds using K[*Cl]Cl and OXONE", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Radiolabeling of aromatic compounds using K[*Cl]Cl and OXONE"}]}, "item_type_id": "8", "owner": "1", "path": ["1"], "permalink_uri": "https://repo.qst.go.jp/records/47672", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-03-21"}, "publish_date": "2017-03-21", "publish_status": "0", "recid": "47672", "relation": {}, "relation_version_is_last": true, "title": ["Radiolabeling of aromatic compounds using K[*Cl]Cl and OXONE"], "weko_shared_id": -1}
Radiolabeling of aromatic compounds using K[*Cl]Cl and OXONE
https://repo.qst.go.jp/records/47672
https://repo.qst.go.jp/records/47672d58f3615-892e-4491-bb21-380260c43485
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2017-03-21 | |||||
タイトル | ||||||
タイトル | Radiolabeling of aromatic compounds using K[*Cl]Cl and OXONE | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Takada, Yuuki
× Takada, Yuuki× Hanyu, Masayuki× Nagatsu, Koutarou× Fukumura, Toshimitsu× 高田 由貴× 破入 正行× 永津 弘太郎× 福村 利光 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We report a novel labeling method for the rapid radiochlorination of aromatic compounds using no-carrier-added short half-life radioactive chloride ions ([38,39Cl]Cl-and [34mCl]Cl-) and OXONE (Sigma-Aldrich, Japan) as an oxidation reagent.The reaction of radioactive chloride ions with anisole in the presence of OXONE gave a mixture of p-[*Cl]chloroanisole and o-[*Cl]-chloroanisole, with a radiochemical conversion yield ofmore than 85%(not decay corrected) and selectivity of 7:3,within 10 min. Regioselective radioactive chlorination was achieved by chlorodestannylation of tributylstannyl compounds to afford the corresponding radiochlorinated compounds (p-chloroanisole and m-chloroanisole) in satisfactory radiochemical yields (80–95% and 46–65%, respectively). | |||||
書誌情報 |
Journal of Labelled Compounds & Radiopharmaceuticals 巻 55, 号 10, p. 383-386, 発行日 2012-08 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0362-4803 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1002/jlcr.2957 |