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  1. 原著論文

Manual on the proper use of meta-[211At] astato-benzylguanidine ([211At] MABG) injections in clinical trials for targeted alpha therapy

https://repo.qst.go.jp/records/86496
https://repo.qst.go.jp/records/86496
920c8a60-e0e0-4acc-b3cb-97456f669b24
Item type 学術雑誌論文 / Journal Article(1)
公開日 2022-07-07
タイトル
タイトル Manual on the proper use of meta-[211At] astato-benzylguanidine ([211At] MABG) injections in clinical trials for targeted alpha therapy
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Ukon, Naoyuki

× Ukon, Naoyuki

WEKO 1058999

Ukon, Naoyuki

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Tatsuya, Higashi

× Tatsuya, Higashi

WEKO 1059000

Tatsuya, Higashi

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Hosono, Makoto

× Hosono, Makoto

WEKO 1059001

Hosono, Makoto

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Kinuya, Seigo

× Kinuya, Seigo

WEKO 1059002

Kinuya, Seigo

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Yamada, Takahiro

× Yamada, Takahiro

WEKO 1059003

Yamada, Takahiro

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Yanagida, Sachiko

× Yanagida, Sachiko

WEKO 1059004

Yanagida, Sachiko

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Namba, Masao

× Namba, Masao

WEKO 1059005

Namba, Masao

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Nakamura, Yoshihide

× Nakamura, Yoshihide

WEKO 1059006

Nakamura, Yoshihide

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Tatsuya, Higashi

× Tatsuya, Higashi

WEKO 1059007

en Tatsuya, Higashi

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抄録
内容記述タイプ Abstract
内容記述 In this manuscript, we present the guideline for use of meta-[211At] astatobenzylguanidine ([211At] MABG), a newly introduced alpha emitting radiopharmaceutical to the up-coming World’s frst clinical trial for targeted alpha therapy (TAT) at Fukushima Medical University in Japan, focusing on radiation safety issues in Japan. This guideline was prepared based on a study supported by the Ministry of Health, Labour, and Welfare, and approved by the Japanese Society of Nuclear Medicine on Oct. 5th, 2021. The study showed that patients receiving [211At] MABG do not need to be admitted to a radiotherapy room
and that TAT using [211At] MABG is possible on an outpatient basis. The radiation exposure from the patient is within the safety standards of the ICRP and IAEA recommendations for the general public and caregivers or patient’s family members.
In this guideline, the following contents are also included: precautions for patients and their families, safety management associated with the use of [211At] MABG, education and training, and disposal of medical radioactive contaminants. TAT using [211At] MABG in Japan should be carried out according to this guideline. Although this guideline is based on the medical environment and laws and regulations in Japan, the issues for radiation protection and evaluation methodology presented in this guideline are useful and internationally acceptable as well.
書誌情報 Annals of Nuclear Medicine

巻 36, p. 695-709, 発行日 2022-06
出版者
出版者 Springer Nature
ISSN
収録物識別子タイプ ISSN
収録物識別子 0914-7187
DOI
識別子タイプ DOI
関連識別子 10.1007/s12149-022-01765-1
関連サイト
識別子タイプ URI
関連識別子 https://trebuchet.public.springernature.app/get_content/cc930489-9ea2-4718-9745-4ff8953ebdab
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