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  1. 原著論文

Deep Learning–based Post Hoc CT Denoising for Myocardial Delayed Enhancement

https://repo.qst.go.jp/records/86406
https://repo.qst.go.jp/records/86406
b8f0b6cb-f4cc-4ec0-a706-a6f4eddabdf0
Item type 学術雑誌論文 / Journal Article(1)
公開日 2022-05-13
タイトル
タイトル Deep Learning–based Post Hoc CT Denoising for Myocardial Delayed Enhancement
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Nishii, Tatsuya

× Nishii, Tatsuya

WEKO 1054165

Nishii, Tatsuya

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Kobayashi, Takuma

× Kobayashi, Takuma

WEKO 1054166

Kobayashi, Takuma

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Tanaka, Hironori

× Tanaka, Hironori

WEKO 1054167

Tanaka, Hironori

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Kotoku, Akiyuki

× Kotoku, Akiyuki

WEKO 1054168

Kotoku, Akiyuki

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Ohta, Yasutoshi

× Ohta, Yasutoshi

WEKO 1054169

Ohta, Yasutoshi

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Morita, Yoshiaki

× Morita, Yoshiaki

WEKO 1054170

Morita, Yoshiaki

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Kensuke, Umehara

× Kensuke, Umehara

WEKO 1054171

Kensuke, Umehara

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Junko, Ota

× Junko, Ota

WEKO 1054172

Junko, Ota

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Horinouchi, Hiroki

× Horinouchi, Hiroki

WEKO 1054173

Horinouchi, Hiroki

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Ishida, Takayuki

× Ishida, Takayuki

WEKO 1054174

Ishida, Takayuki

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Fukuda, Tetsuya

× Fukuda, Tetsuya

WEKO 1054175

Fukuda, Tetsuya

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Kensuke, Umehara

× Kensuke, Umehara

WEKO 1054176

en Kensuke, Umehara

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Junko, Ota

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WEKO 1054177

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抄録
内容記述タイプ Abstract
内容記述 Background
To improve myocardial delayed enhancement (MDE) CT, a deep learning (DL)–based post hoc denoising method supervised with averaged MDE CT data was developed.

Purpose
To assess the image quality of denoised MDE CT images and evaluate their diagnostic performance by using late gadolinium enhancement (LGE) MRI as a reference.

Materials and methods
MDE CT data obtained by averaging three acquisitions with a single breath hold 5 minutes after the contrast material injection in patients from July 2020 to October 2021 were retrospectively reviewed. Preaveraged images obtained in 100 patients as inputs and averaged images as ground truths were used to supervise a residual dense network (RDN). The original single-shot image, standard averaged image, RDN-denoised original (DLoriginal) image, and RDN-denoised averaged (DLave) image of holdout cases were compared. In 40 patients, the CT value and image noise in the left ventricular cavity and myocardium were assessed. The segmental presence of MDE in the remaining 40 patients who underwent reference LGE MRI was evaluated. The sensitivity, specificity, and accuracy of each type of CT image and the improvement in accuracy achieved with the RDN were assessed using odds ratios (ORs) estimated with the generalized estimation equation.

Results
Overall, 180 patients (median age, 66 years [IQR, 53–74 years]; 107 men) were included. The RDN reduced image noise to 28% of the original level while maintaining equivalence in the CT values (P < .001 for all). The sensitivity, specificity, and accuracy of the original images were 77.9%, 84.4%, and 82.3%, of the averaged images were 89.7%, 87.9%, and 88.5%, of the DLoriginal images were 93.1%, 87.5%, and 89.3%, and of the DLave images were 95.1%, 93.1%, and 93.8%, respectively. DLoriginal images showed improved accuracy compared with the original images (OR, 1.8 [95% CI: 1.2, 2.9]; P = .011) and DLave images showed improved accuracy compared with the averaged images (OR, 2.0 [95% CI: 1.2, 3.5]; P = .009).

Conclusion
The proposed denoising network supervised with averaged CT images reduced image noise and improved the diagnostic performance for myocardial delayed enhancement CT.
書誌情報 Radiology

p. 1-10, 発行日 2022-06
出版者
出版者 Radiological Society of North America
ISSN
収録物識別子タイプ ISSN
収録物識別子 0033-8419
PubMed番号
識別子タイプ PMID
関連識別子 35762889
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1148/radiol.220189
関連サイト
識別子タイプ URI
関連識別子 https://pubs.rsna.org/doi/full/10.1148/radiol.220189
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