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  1. 原著論文

Impacts of psychological stress on high dose-rate radiation acute effects in a mouse experimental model

https://repo.qst.go.jp/records/86390
https://repo.qst.go.jp/records/86390
797db8d4-b9e5-45c7-952e-7e9df44eb417
Item type 学術雑誌論文 / Journal Article(1)
公開日 2022-06-27
タイトル
タイトル Impacts of psychological stress on high dose-rate radiation acute effects in a mouse experimental model
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Tetsuo, Nakajima

× Tetsuo, Nakajima

WEKO 1059171

Tetsuo, Nakajima

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Yasuharu, Ninomiya

× Yasuharu, Ninomiya

WEKO 1059172

Yasuharu, Ninomiya

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Takamitsu, Morioka

× Takamitsu, Morioka

WEKO 1059173

Takamitsu, Morioka

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Mayumi, Nishimura

× Mayumi, Nishimura

WEKO 1059174

Mayumi, Nishimura

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Shizuko, Kakinuma

× Shizuko, Kakinuma

WEKO 1059175

Shizuko, Kakinuma

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Tetsuo, Nakajima

× Tetsuo, Nakajima

WEKO 1059176

en Tetsuo, Nakajima

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Yasuharu, Ninomiya

× Yasuharu, Ninomiya

WEKO 1059177

en Yasuharu, Ninomiya

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Takamitsu, Morioka

× Takamitsu, Morioka

WEKO 1059178

en Takamitsu, Morioka

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Mayumi, Nishimura

× Mayumi, Nishimura

WEKO 1059179

en Mayumi, Nishimura

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Shizuko, Kakinuma

× Shizuko, Kakinuma

WEKO 1059180

en Shizuko, Kakinuma

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抄録
内容記述タイプ Abstract
内容記述 Psychological stress affects health. Radiation workers in the medical field or astronauts living in space have possible risks of exposure to radiation, and psychological stress is considered to be easily induced in them due to activities performed in small areas or stress conditions. The impact of psychological stress on the effects of radiation was evaluated in senescence-accelerated mouse prone 10 (SAMP10) mice and ddY mice using a confrontational housing model, which makes dominant and subordinate mice in a cage live together without severe quarrel. Mice of ddY and SAMP10 have been previously demonstrated to be influenced in terms of acute and late effects, respectively, under psychological stress by this model. In SAMP10 mice, irradiation with 4 Gy induced the death of irradiated mice under psychological stress. In ddY mice, irradiation with 5 Gy X-rays alone had almost no effect on the mouse survival, but irradiation in conditions of psychological stress promoted acute death of irradiated mice. In addition, hypocellular bone marrow was also observed histopathologically in irradiated ddY mice under stress. Psychological stress may promote damage caused by radiation through modulation of radio-sensitivity in bone marrow in mice. This model would be useful for evaluation of modulation of radiation-induced various effects by psychological stress.
書誌情報 Journal of Radiation Research

巻 63, 号 4, p. 602-608, 発行日 2022-06
出版者
出版者 Oxford University Press
ISSN
収録物識別子タイプ ISSN
収録物識別子 1349-9157
PubMed番号
識別子タイプ PMID
関連識別子 35726341
DOI
識別子タイプ DOI
関連識別子 10.1093/jrr/rrac028
関連サイト
識別子タイプ URI
関連識別子 https://academic.oup.com/jrr/advance-article/doi/10.1093/jrr/rrac028/6611800?guestAccessKey=90ae95ca-a3aa-4e95-93b6-226e047fd31f
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