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Features of accelerator-based neutron source for boron neutron capture therapy calculated by Particle and Heavy Ion Transport code System (PHITS)
https://repo.qst.go.jp/records/85637
https://repo.qst.go.jp/records/856375df05ddc-1def-4c62-ad5e-24f3db69dd9a
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2022-02-22 | |||||
タイトル | ||||||
タイトル | Features of accelerator-based neutron source for boron neutron capture therapy calculated by Particle and Heavy Ion Transport code System (PHITS) | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Matsuya, Yusuke
× Matsuya, Yusuke× Tamon, Kusumoto× Yachi, Yoshie× Hirata, Yuho× Miwa, Misako× Ishikawa, Masayori× Date, Hiroyuki× Iwamoto, Yosuke× Matsuyama, Shigeo× Fukunaga, Hisanori× Tamon, Kusumoto |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Accelerator-based neutron sources have been developed and installed in recent decades for boron neutron capture therapy (BNCT) in several clinical facilities. Lithium is one of the targets that can produce epithermal neutrons from the 7 Li(p,n)7 Be near-threshold reaction, and accelerator-based BNCT systems employing a Li target are promising for cancer treatment. The accurate evaluation of the characteristics of an accelerator-based neutron source is a key to estimating the therapeutic effects of the accelerator-based BNCT. Particle and Heavy Ion Transport code System (PHITS) is a general-purpose Monte Carlo code, which can simulate a variety of diverse particle types and nuclear reactions. The latest PHITS code enables simulating the generation of neutrons from the 7 Li(p,n)7 Be reactions by using the Japanese Evaluated Nuclear Data Library 4.0 high-energy file. Thus, the PHITS code can be adopted for dose estimation during treatment planning for the accelerator-based BNCT. In this study, we evaluated the neutron fluence using the PHITS code by comparing it to reference data. The subsequent neutron transport simulations were performed to evaluate the boron trifluoride detector responses and the recoiled proton fluence detected by a CR-39 plastic detector. These comparative studies confirmed that the PHITS code can accurately simulate neutrons generated from an accelerator using a Li target. The PHITS code has a significant potential for a detailed evaluation of neutron fields and for predicting the therapeutic effects of the accelerator-based BNCT. |
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書誌情報 |
AIP Advances 巻 12, p. 025013, 発行日 2022-02 |
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出版者 | ||||||
出版者 | American Institute of Physics | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2158-3226 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1063/5.0077782 | |||||
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識別子タイプ | URI | |||||
関連識別子 | https://aip.scitation.org/doi/10.1063/5.0077782 |