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Performance improvement of Compton imaging of astatine-211 by optimising coincidence time windows
https://repo.qst.go.jp/records/84859
https://repo.qst.go.jp/records/84859410e22e0-9c39-4c32-b9ad-97855c12cd8e
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-09-28 | |||||
| タイトル | ||||||
| タイトル | Performance improvement of Compton imaging of astatine-211 by optimising coincidence time windows | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Nagao, Yuto
× Nagao, Yuto× Yamaguchi, Mitsutaka× Watanabe, Shigeki× S. Ishioka, Noriko× Kawachi, Naoki× Watabe, Hiroshi× Yuuto, Nagao× Mitsutaka, Yamaguchi× Shigeki, Watanabe× Noriko, Ishioka× Naoki, Kawachi× Hiroshi, Watabe |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Astatine-211 is one of the promising radioisotopes for targeted alpha therapy. Optimising treatment strategies as well as determining the suitability of a given agent for a particular patient requires to image the time-dependent distribution of the targeted radiotherapeutic agent both in tumours and in normal tissues. Since the biodistribution of astatine is different from that of iodine, imaging astatine-211 directly is essential. In the previous study of astatine-211 Compton imaging, random coincidence events due to polonium K-shell X-rays were dominant and seemed to cause saturation of counts. Thus optimisation of the coincidence time windows is important to reduce random coincidence events. In this study, we have optimised the coincidence time windows of a Compton camera and improved the sensitivity, noise and spatial resolution of astatine-211 imaging. | |||||
| 書誌情報 |
Journal of Instrumentation 巻 16, 号 12, p. C12031, 発行日 2021-12 |
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| 出版者 | ||||||
| 出版者 | Institute of Physics | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1748-0221 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1088/1748-0221/16/12/C12031 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://iopscience.iop.org/article/10.1088/1748-0221/16/12/C12031 | |||||
