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Controlling Major Portal Vein Invasion Progression during Lenvatinib Treatment by Carbon-Ion Radiotherapy in Patients with Advanced Hepatocellular Carcinoma
https://repo.qst.go.jp/records/84808
https://repo.qst.go.jp/records/848082fb5d910-badc-439f-b94f-d91d755dc9d1
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-09-28 | |||||
| タイトル | ||||||
| タイトル | Controlling Major Portal Vein Invasion Progression during Lenvatinib Treatment by Carbon-Ion Radiotherapy in Patients with Advanced Hepatocellular Carcinoma | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Yoshida, Ryoi
× Yoshida, Ryoi× Koroki, Keisuke× Makishima, Hirokazu× Ogasawara, Sadahisa× Ishino, Takamasa× Ogawa, Keita× Nakagawa, Miyuki× Fujiwara, Kisako× Hidemi Unozawa× Iwanaga, Terunao× Fujita, Naoto× Sakuma, Takafumi× Kanzaki, Hiroaki× Kobayashi, Kazufumi× Kanogawa, Naoya× Kiyono, Soichiro× Nakamura, Masato× Kondo, Takayuki× Saito, Tomoko× Nakagawa, Ryo× Suzuk, Eiichiro× Ooka, Yoshihiko× Nakamoto, Shingo× Tawada, Akinobu× Chiba, Tetsuhiro× Arai, Makoto× Kaneko, Takashi× Wakatsuki, Masaru× Kato, Jun× Tsuji, Hiroshi× Kato, Naoya× Hirokazu, Makishima× Keita, Ogawa× Naoto, Fujita× Naoya, Kanogawa× Tomoko, Saitou× Takashi, Kaneko× Masaru, Wakatsuki× Hiroshi, Tsuji× Kato, Naoya |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Macrovascular invasion (MVI), including portal vein tumor thrombosis (PVTT), is strongly associated with poor prognosis in patients with hepatocellular carcinoma (HCC). While recommended standard treatment for patients with advanced HCC is systemic therapy, various treatment approaches, including resection, transarterial chemoembolization, and radiation, have been empirically suggested to improve prognosis by eliminating or controlling MVI. Herein, we report our experience of a case with advanced HCC where MVI was controlled by carbon-ion radiotherapy (CIRT) while on systemic therapy, resulting in a prolonged survival. A female patient with HCC in her early 60s had multiple intrahepatic lesions (maximum 60 mm in diameter) with PVTT. The PVTT of this patient had reached the main trunk of the portal vein despite the use of lenvatinib. The other intrahepatic lesions of the patient, except PVTT, had been controlled by lenvatinib. Therefore, hoping to control PVTT, we attempted CIRT. The patient resumed lenvatinib therapy after the irradiation. During lenvatinib re-treatment, no evident progression of PVTT was observed in the patient. | |||||
| 書誌情報 |
Case Reports in Oncology 巻 14, p. 1103-1110, 発行日 2021-07 |
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| 出版者 | ||||||
| 出版者 | Karger Publishers | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1662-6575 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1159/000517440 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.karger.com/Article/FullText/517440 | |||||
