{"_buckets": {"deposit": "27efb2d8-2c1c-432e-b050-0fe80839cf18"}, "_deposit": {"created_by": 1, "id": "84727", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "84727"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00084727", "sets": ["1"]}, "author_link": ["1022409", "1022418", "1022398", "1022414", "1022396", "1022408", "1022410", "1022405", "1022411", "1022407", "1022417", "1022400", "1022415", "1022413", "1022399", "1022402", "1022397", "1022412", "1022416", "1022401", "1022395", "1022406", "1022403", "1022404"], "item_8_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2021-06", "bibliographicIssueDateType": "Issued"}, "bibliographicPageStart": "667881", "bibliographicVolumeNumber": "12", "bibliographic_titles": [{"bibliographic_title": "Frontiers in psychiatry"}]}]}, "item_8_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Large-scale neuroimaging data acquired and shared by multiple institutions are essential to advance neuroscientific understanding of pathophysiological mechanisms in psychiatric disorders, such as major depressive disorder (MDD). About 75% of studies that have applied machine learning technique to neuroimaging have been based on diagnoses by clinicians. However, an increasing number of studies have highlighted the difficulty in finding a clear association between existing clinical diagnostic categories and neurobiological abnormalities. Here, using resting-state functional magnetic resonance imaging, we determined and validated resting-state functional connectivity related to depression symptoms that were thought to be directly related to neurobiological abnormalities. We then compared the resting-state functional connectivity related to depression symptoms with that related to depression diagnosis that we recently identified. In particular, for the discovery dataset with 477 participants from 4 imaging sites, we removed site differences using our recently developed harmonization method and developed a brain network prediction model of depression symptoms (Beck Depression Inventory-II [BDI] score). The prediction model significantly predicted BDI score for an independent validation dataset with 439 participants from 4 different imaging sites. Finally, we found 3 common functional connections between those related to depression symptoms and those related to MDD diagnosis. These findings contribute to a deeper understanding of the neural circuitry of depressive symptoms in MDD, a hetero-symptomatic population, revealing the neural basis of MDD.", "subitem_description_type": "Abstract"}]}, "item_8_relation_13": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "34177657", "subitem_relation_type_select": "PMID"}}]}, "item_8_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "10.3389/fpsyt.2021.667881", "subitem_relation_type_select": "DOI"}}]}, "item_8_relation_17": {"attribute_name": "関連サイト", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.frontiersin.org/articles/10.3389/fpsyt.2021.667881", "subitem_relation_type_select": "URI"}}]}, "item_8_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1664-0640", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yamashita, Ayumu"}], "nameIdentifiers": [{"nameIdentifier": "1022395", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sakai, Yuki"}], "nameIdentifiers": [{"nameIdentifier": "1022396", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamada, Takashi"}], "nameIdentifiers": [{"nameIdentifier": "1022397", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yahata, Noriaki"}], "nameIdentifiers": [{"nameIdentifier": "1022398", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kunimatsu, Akira"}], "nameIdentifiers": [{"nameIdentifier": "1022399", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okada, Naohiro"}], "nameIdentifiers": [{"nameIdentifier": "1022400", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Itahashi, Takashi"}], "nameIdentifiers": [{"nameIdentifier": "1022401", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hashimoto, Ryuichiro"}], "nameIdentifiers": [{"nameIdentifier": "1022402", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mizuta, Hiroto"}], "nameIdentifiers": [{"nameIdentifier": "1022403", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ichikawa, Naho"}], "nameIdentifiers": [{"nameIdentifier": "1022404", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takamura, Masahiro"}], "nameIdentifiers": [{"nameIdentifier": "1022405", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okada, Go"}], "nameIdentifiers": [{"nameIdentifier": "1022406", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamagata, Hirotaka"}], "nameIdentifiers": [{"nameIdentifier": "1022407", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Harada, Kenichiro"}], "nameIdentifiers": [{"nameIdentifier": "1022408", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsuo, Koji"}], "nameIdentifiers": [{"nameIdentifier": "1022409", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "C Tanaka, Saori"}], "nameIdentifiers": [{"nameIdentifier": "1022410", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawato, Mitsuo"}], "nameIdentifiers": [{"nameIdentifier": "1022411", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kasai, Kiyoto"}], "nameIdentifiers": [{"nameIdentifier": "1022412", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kato, Nobumasa"}], "nameIdentifiers": [{"nameIdentifier": "1022413", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takahashi, Hidehiko"}], "nameIdentifiers": [{"nameIdentifier": "1022414", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okamoto, Yasumasa"}], "nameIdentifiers": [{"nameIdentifier": "1022415", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamashita, Okito"}], "nameIdentifiers": [{"nameIdentifier": "1022416", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Imamizu, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "1022417", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Noriaki, Yahata", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1022418", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Common Brain Networks Between Major Depressive-Disorder Diagnosis and Symptoms of Depression That Are Validated for Independent Cohorts.", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Common Brain Networks Between Major Depressive-Disorder Diagnosis and Symptoms of Depression That Are Validated for Independent Cohorts."}]}, "item_type_id": "8", "owner": "1", "path": ["1"], "permalink_uri": "https://repo.qst.go.jp/records/84727", "pubdate": {"attribute_name": "公開日", "attribute_value": "2021-10-04"}, "publish_date": "2021-10-04", "publish_status": "0", "recid": "84727", "relation": {}, "relation_version_is_last": true, "title": ["Common Brain Networks Between Major Depressive-Disorder Diagnosis and Symptoms of Depression That Are Validated for Independent Cohorts."], "weko_shared_id": -1}