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Development of a neutron camera system to visualize the dose distribution by secondary neutrons for safer proton therapy
https://repo.qst.go.jp/records/84597
https://repo.qst.go.jp/records/84597a5707675-25ea-4103-a026-43c458c9540a
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-10-06 | |||||
| タイトル | ||||||
| タイトル | Development of a neutron camera system to visualize the dose distribution by secondary neutrons for safer proton therapy | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Tanaka, R.
× Tanaka, R.× Kataoka, J.× Nishi, F.× Yokokawa, H.× Taku, Inaniwa× Taku, Inaniwa |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Proton therapy has recently garnered significant attention as an effective treatment for cancer that can effectively damage tumor tissues while reducing doses to healthy tissues and organs. However, secondary neutrons generated by interactions with protons and brass collimators or the patient's body may cause harm to the human body. Nevertheless, the risks are yet to be precisely assessed or reflected in actual treatment plans. In this study, we develop a novel neutron camera that enables the visualization of spatial dose distribution by secondary neutrons. First, a neutron camera comprising two layers of units is constructed; each of the layer is composed of a plastic scintillator coupled with a photomultiplier tube. As a preliminary experiment, it is confirmed that the developed camera can visualize fission neutrons from a252Cf source. Subsequently, secondary neutrons are observed from a brass (imitating the brass collimator) and water (imitating the patient's body) phantom irradiated with a 70 MeV proton beam, in which the neutron camera is placed at 0∘, 15∘ (only in the case of brass) and 30∘ from each phantom 30 cm ahead. Following neutron/gamma event selections using two methods, i.e., time of flight and pulse shape discrimination, each of the reconstructed images successfully converged at the correct positions, with average angular resolutions of 21∘(brass, full width at half maximum (FWHM)) and 19∘ (water, FWHM). Furthermore, dosimetry using the G(E) function method is applied to the images, enabling a dose distribution image to be created using secondary neutrons. As a result, the evaluated dose rate is 307 μSv/min for brass and 88.1 μSv/min for water, which are 86 % and 64 % those of the simulated dose rates, respectively. Eventually, future tasks for the utilization of the camera in actual proton therapy are discussed. | |||||
| 書誌情報 |
Journal of Instrumentation 巻 16, p. P06004, 発行日 2021-06 |
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| 出版者 | ||||||
| 出版者 | IOP Publishing | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1748-0221 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1088/1748-0221/16/06/P06004 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://iopscience.iop.org/article/10.1088/1748-0221/16/06/P06004 | |||||
