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Microheater-integrated zinc oxide nanowire microfluidic device for hybridization-based detection of target single-stranded DNA
https://repo.qst.go.jp/records/84588
https://repo.qst.go.jp/records/84588e6ce14e1-d92f-43fb-b44a-01f46af212a3
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-10-01 | |||||
| タイトル | ||||||
| タイトル | Microheater-integrated zinc oxide nanowire microfluidic device for hybridization-based detection of target single-stranded DNA | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Takahashi, Hiromi
× Takahashi, Hiromi× Yasui, Takao× Kashida, Hiromu× Makino, Koki× Shinjo, Keiko× Liu, Quanli× Shimada, Taisuke× Rahong, Sakon× Kaji, Noritada× Asanuma, Hiroyuki× Baba, Yoshinobu× Yoshinobu, Baba |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Detection of cell-free DNA (cfDNA) has an impact on DNA analysis in liquid biopsies. However, current strategies to detect cfDNA have limitations that should be overcome, such as having low sensitivity and requiring much time and a specialized instrument. Thus, non-invasive and rapid detection tools are needed for disease prevention and early-stage treatment. Here we developed a device having a microheater integrated with zinc oxide nanowires (microheater-ZnO-NWs) to detect target single-stranded DNAs (ssDNAs) based on DNA probe hybridization. We confirmed experimentally that our device realized in-situ annealed DNA probes by which we subsequently detected target ssDNAs. We envision that this device can be utilized for fundamental studies related to nanobiodevice-based DNA detection. | |||||
| 書誌情報 |
Nanotechnology 巻 32, 号 25, p. 255301, 発行日 2021-04 |
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| 出版者 | ||||||
| 出版者 | IOP Publishing | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0957-4484 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1088/1361-6528/abef2c | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://iopscience.iop.org/article/10.1088/1361-6528/abef2c | |||||
