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  1. 学会発表・講演等
  2. 口頭発表

Comparison of two small animal PET prototypes for off-line range verification in carbon beam irradiation

https://repo.qst.go.jp/records/83760
https://repo.qst.go.jp/records/83760
3387ebad-4404-4d67-abdf-d2c2e4f63bee
Item type 会議発表用資料 / Presentation(1)
公開日 2021-10-06
タイトル
タイトル Comparison of two small animal PET prototypes for off-line range verification in carbon beam irradiation
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Hideaki, Tashima

× Hideaki, Tashima

WEKO 1009652

Hideaki, Tashima

Search repository
Mohammadi, Akram

× Mohammadi, Akram

WEKO 1009653

Mohammadi, Akram

Search repository
Fumihiko, Nishikido

× Fumihiko, Nishikido

WEKO 1009654

Fumihiko, Nishikido

Search repository
Kang, Hangyu

× Kang, Hangyu

WEKO 1009655

Kang, Hangyu

Search repository
Go, Akamatsu

× Go, Akamatsu

WEKO 1009656

Go, Akamatsu

Search repository
Sodai, Takyu

× Sodai, Takyu

WEKO 1009657

Sodai, Takyu

Search repository
Yuma, Iwao

× Yuma, Iwao

WEKO 1009658

Yuma, Iwao

Search repository
Shinji, Sato

× Shinji, Sato

WEKO 1009659

Shinji, Sato

Search repository
Hitoshi, Ishikawa

× Hitoshi, Ishikawa

WEKO 1009660

Hitoshi, Ishikawa

Search repository
Taiga, Yamaya

× Taiga, Yamaya

WEKO 1009661

Taiga, Yamaya

Search repository
Hideaki, Tashima

× Hideaki, Tashima

WEKO 1009662

en Hideaki, Tashima

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Mohammadi, Akram

× Mohammadi, Akram

WEKO 1009663

en Mohammadi, Akram

Search repository
Fumihiko, Nishikido

× Fumihiko, Nishikido

WEKO 1009664

en Fumihiko, Nishikido

Search repository
Kang, Hangyu

× Kang, Hangyu

WEKO 1009665

en Kang, Hangyu

Search repository
Go, Akamatsu

× Go, Akamatsu

WEKO 1009666

en Go, Akamatsu

Search repository
Sodai, Takyu

× Sodai, Takyu

WEKO 1009667

en Sodai, Takyu

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Yuma, Iwao

× Yuma, Iwao

WEKO 1009668

en Yuma, Iwao

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Shinji, Sato

× Shinji, Sato

WEKO 1009669

en Shinji, Sato

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Hitoshi, Ishikawa

× Hitoshi, Ishikawa

WEKO 1009670

en Hitoshi, Ishikawa

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Taiga, Yamaya

× Taiga, Yamaya

WEKO 1009671

en Taiga, Yamaya

Search repository
抄録
内容記述タイプ Abstract
内容記述 Small animal studies in the carbon ion therapy field are still necessary to understand cancer cell behavior deeply and to explore new medical applications. For precise irradiation with dose monitoring for small animals, PET measurement of positron emitters produced via fragmentation reactions is desired. This study compared our two recently developed small animal PET prototypes with different performance characteristics. The first is a total body small-animal (TBS) PET prototype with a high sensitivity of 16.7% at the center, while the spatial resolution is limited to about 2 mm. The second is a crosshair light sharing (CLS) PET prototype having sub-millimeter spatial resolution while the sensitivity at the center is limited to 1.0%. Both are compact mobile scanners, which can be moved to an irradiation room at the Heavy-Ion Medical Accelerator in Chiba (HIMAC) for offline PET measurement. Also, they have sufficient axial length for measuring a rat's total body at one time. In this study, cylindrical phantoms of 4 cm diameter and 10 cm length made of polymethyl methacrylate (PMMA) were irradiated with a 290 MeV/u 12C beam (1.2×109 pps) for 16 s. A brass collimator and a PMMA range shifter of 90 mm thickness were placed upstream to adjust the beam shape and the Bragg peak position to the phantom center. Off-line PET measurement start times after the end of irradiation and the measurement times were 5 min and 20 min for TBS PET and 6 min and 30 min for CLS PET, respectively. As a result, peaks in images obtained by TBS and CLS PET prototypes were observed respectively at 4 mm and 3 mm upstream from the Bragg peak position. The obtained image of the CLS PET was significantly noisier than that of TBS PET, although the measurement time of CLS PET was longer. The high sensitivity of the TBS PET prototype is preferred in cases where the number of produced positron emitters is limited.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 IEEE NSS MIC 2021
発表年月日
日付 2021-10-23
日付タイプ Issued
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