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マイクロビームと組織培養を用いた放射線組織生物学―保健物理学と放射線生物学の接点として
https://repo.qst.go.jp/records/82441
https://repo.qst.go.jp/records/8244106d4adfb-a98e-450a-a7a5-185e7d42dc48
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-03-23 | |||||
| タイトル | ||||||
| タイトル | マイクロビームと組織培養を用いた放射線組織生物学―保健物理学と放射線生物学の接点として | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
福永, 久典
× 福永, 久典× 横谷, 明徳× Akinari, Yokoya |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Tissue is a complex system with a highly dynamic structure to maintain a stable internal environment. The homeostatic mechanisms could be involved in radiation-induced effects at the tissue level. Also, tissue-weighting factors have been regarded as an essential index for the guideline released from the International Committee on Radiological Protection. Thus, for both radiobiology and health physics, it is important to understand radiation-induced tissue-level responses. The applications of microbeams and tissue cultures illustrated in this article focus on their relevance to radiation tissue biology that provides a novel approach for greater accuracy in risk assessment of radiation exposure. We review on recent progress in both microbeams and tissue cultures, which is promising for providing novel insights into radiation tissue biology. In addition, we present the use of ex vivo mouse testicular tissue culture as an experimental model of spermatogenesis to investigate radiobiological effects with microbeams. Our model represents a unique application in the field, with significant potential for deeper mechanistic insight into radiation-induced tissue-level effects and appropriate radiological protection. | |||||
| 書誌情報 |
保健物理 巻 55, 号 2, p. 92-96, 発行日 2021-03 |
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| 関連サイト | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.5453/jhps.55.92 | |||||
