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Extracellular vesicles released from irradiated neonatal mouse cheek tissue increased cell survival after radiation
https://repo.qst.go.jp/records/81989
https://repo.qst.go.jp/records/8198907cb3807-4a90-46f3-8683-9af42cbddf15
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-02-24 | |||||
| タイトル | ||||||
| タイトル | Extracellular vesicles released from irradiated neonatal mouse cheek tissue increased cell survival after radiation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kentaro, Ariyoshi
× Kentaro, Ariyoshi× Yota, Hiroyama× Naoya, Fujiwara× Tomisato, Miura× Kosuke, Kasai× Akifumi, Nakata× Yohei, Fujishima× Swee Ting Goh, Valeria× Mitsuaki, Yoshida× Yota, Hiroyama |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Alopecia is one of the common symptoms after high-dose radiation exposure. In our experiments, neonatal mice that received 7 Gy X-ray exhibited defects in overall hair growth, except for their cheeks. This phenomenon might suggest that some substances were secreted and prevented hair follicle loss in the infant tissues around their cheeks after radiation damage. In this study, we focused on exosome-like vesicles (ELV) secreted from cheek skin tissues and back skin tissues, as control, and examined their radiation protective effects on mouse fibroblast cell lines. We observed that ELV from irradiated cheek skin showed protective effects from radiation. Our results suggest that ELV from radiation-exposed cheek skin tissue is one of the secreted factors that prevent hair follicle loss after high-dose radiation. | |||||
| 書誌情報 |
Journal of radiation research 巻 62, 号 1, p. 73-78, 発行日 2021-01 |
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| 出版者 | ||||||
| 出版者 | Oxford University Press | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1349-9157 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 33302296 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1093/jrr/rraa106 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://academic.oup.com/jrr/article/62/1/73/6030104 | |||||
