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Design of Nuclear Magnetic Resonance Molecular Probes for Hyperpolarized Bioimaging
https://repo.qst.go.jp/records/80900
https://repo.qst.go.jp/records/809000558cfda-d419-4837-9357-a0e5316dcd54
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-11-05 | |||||
タイトル | ||||||
タイトル | Design of Nuclear Magnetic Resonance Molecular Probes for Hyperpolarized Bioimaging | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Kondo, Yohei
× Kondo, Yohei× Nonaka, Hiroshi× Takakusagi, Yoichi× Sando, Shinsuke× Yoichi, Takakusagi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Nuclear hyperpolarization has emerged as a method to dramatically enhance the sensitivity of NMR. By applying this powerful tool, small molecules with stable isotopes have been subjected to highly sensitive biomedical molecular imaging. The recent development of molecular probes for hyperpolarized in vivo analysis has demonstrated the ability of this technique to provide unique metabolic and physiological information. This review presents a brief introduction of hyperpolarization technology, approaches to rational design of molecular probes for hyperpolarized analysis, and examples of molecules that have met with in vitro or in vivo success. | |||||
書誌情報 |
Angewandte Chemie (International ed. in English) 巻 60, 号 27, p. 14779-14799, 発行日 2020-11 |
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出版者 | ||||||
出版者 | Wiley-VCH | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1433-7851 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 32372551 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1002/anie.201915718 | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201915718 |