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Radiotheranostic Agent 64Cu-cyclam-RAFT-c(-RGDfK-)4 for Management of Peritoneal Metastasis in Ovarian Cancer
https://repo.qst.go.jp/records/80890
https://repo.qst.go.jp/records/808906ca960f3-aec0-46d3-8e5c-50b4ee7e234d
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-09-17 | |||||
| タイトル | ||||||
| タイトル | Radiotheranostic Agent 64Cu-cyclam-RAFT-c(-RGDfK-)4 for Management of Peritoneal Metastasis in Ovarian Cancer | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Zhao-Hui, Jin
× Zhao-Hui, Jin× B Tsuji, Atsushi× Mélissa, Degardin× Sugyo, Aya× Obara, Satoshi× Wakizaka, Hidekatsu× Nagatsu, Kotaro× Hu, Kuan× Ming-Rong, Zhang× Dumy, Pascal× Boturyn, Didier× Higashi, Tatsuya× Zhao-Hui, Jin× Atsushi, Tsuji× Aya, Sugyo× Satoshi, Obara× Hidekatsu, Wakizaka× Kotaro, Nagatsu× Kuan, Hu× Zhang, Ming-Rong× Tatsuya, Higashi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Ovarian cancer peritoneal metastases (OCPMs) are a pathophysiologically heterogeneous group of tumors that are rarely curable. αvβ3 integrin (αvβ3) is overexpressed on tumoral neovessels and frequently on ovarian cancer cells. Here, using two clinically relevant αvβ3-positive OCPM mouse models, we studied the theranostic potential of an αvβ3-specific radiopeptide, 64Cu-cyclam-RAFT-c(-RGDfK-)4 (64Cu-RaftRGD), and its intra- and intertumoral distribution in relation to the tumor microenvironment. | |||||
| 書誌情報 |
Clinical Cancer Research 巻 26, 号 23, p. 6230-6241, 発行日 2020-09 |
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| 出版者 | ||||||
| 出版者 | AACR | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1078-0432 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 32933998 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1158/1078-0432.CCR-20-1205 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://clincancerres.aacrjournals.org/content/26/23/6230 | |||||
