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Non-invasive imaging of radiocesium dynamics in a living animal using a positron-emitting 127Cs tracer
https://repo.qst.go.jp/records/80719
https://repo.qst.go.jp/records/80719bab15439-ef7b-46ce-9e7f-28d4559a3139
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-09-18 | |||||
タイトル | ||||||
タイトル | Non-invasive imaging of radiocesium dynamics in a living animal using a positron-emitting 127Cs tracer | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Suzui, Nobuo
× Suzui, Nobuo× Takuya, Shibata (JAEA)× Yin, Yonggen× Yoshihito, Funaki (Tohoku University)× Keisuke, Kurita (JAEA)× Hoshina, Hiroyuki× Yamaguchi, Mitsutaka× Fujimaki, Shu× Seko, Noriaki× Hiroshi, Watabe (Tohoku University)× Kawachi, Naoki× Nobuo, Suzui× Yin, Yonggen× Hiroyuki, Hoshina× Mitsutaka, Yamaguchi× Shu, Fujimaki× Noriaki, Seko× Naoki, Kawachi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Visualizing the dynamics of cesium (Cs) is desirable to understand the impact of radiocesium when accidentally ingested or inhaled by humans. However, visualization of radiocesium in vivo is currently limited to plants. Herein, we describe a method for the production and purification of 127Cs and its use in visualizing Cs dynamics in a living animal. The positron-emitting nuclide 127Cs was produced using the 127I (α, 4n) 127Cs reaction, which was induced by irradiation of sodium iodide with a 4He2+ beam from a cyclotron. We excluded sodium ions by using a material that specifically adsorbs Cs as a purification column and successfully eluted 127Cs by flowing a solution of ammonium sulfate into the column. We injected the purified 127Cs tracer solution into living rats and the dynamics of Cs were visualized using positron emission tomography; the distributional images showed the same tendency as the results of previous studies using disruptive methods. Thus, this method is useful for the non-invasive investigation of radiocesium in a living animal. | |||||
書誌情報 |
Scientific Reports 巻 10, p. 16155, 発行日 2020-10 |
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出版者 | ||||||
出版者 | Nature | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2045-2322 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1038/s41598-020-73351-2 | |||||
関連サイト | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1038/s41598-020-73351-2 |