WEKO3
アイテム
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Proton Therapy for Primary Renal Cell Carcinoma: The First Nationwide Retrospective Study in Japan
https://repo.qst.go.jp/records/80677
https://repo.qst.go.jp/records/80677a9bd06a9-cc10-48fc-8c72-033cc9332ae0
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-10-08 | |||||
タイトル | ||||||
タイトル | Proton Therapy for Primary Renal Cell Carcinoma: The First Nationwide Retrospective Study in Japan | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
FUKUMITSU, NOBUYOSHI
× FUKUMITSU, NOBUYOSHI× Ishikawa, Hitoshi× ARIMURA, TAKESHI× WADA, HITOSHI× Okimoto, Tomoaki× Satou, Yoshitaka× Iwata, Hiromitsu× SHIMIZU, SHOSEI× Sakurai, Hideyuki× Hitoshi, Ishikawa× Tomoaki, Okimoto× Yoshitaka, Satou× Hiromitsu, Iwata× Hideyuki, Sakurai |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background/aim: This multi-institutional study aimed to investigate the efficacy and feasibility of proton beam therapy (PBT) for renal cell carcinoma (RCC) in Japan. Patients and methods: The survival, local control, and toxicities in 22 RCC patients treated between 2001 and 2016 at 6 Japanese PBT institutes were analyzed. Results: The 22 patients comprised 20 men and had a median age of 67 (range=42-88) years. The total irradiation dose was 60-79.6 Gy (relative biological effectiveness). Over a median follow-up of 37 months, the 3-year overall and disease-specific survival rates were 95% and 100%, respectively, and no recurrence occurred. No patient experienced grade 3 or higher adverse events. The serum blood urea nitrogen (p=0.25) and creatinine levels (p=0.95) were not significantly affected, although the mean estimated glomerular filtration rate was reduced by 7.1±11.2 ml/min/1.73 m2 Conclusion: Despite the small number of patients, high-dose PBT can control RCC while maintaining their renal function with high probability, and could be and alternative curative therapy especially for inoperable patients. |
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書誌情報 |
in vivo 巻 34, 号 5, p. 2883-2889, 発行日 2020-10 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0258-851X | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 32871828 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.21873/invivo.12116 | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://iv.iiarjournals.org/content/34/5/2883.full |