WEKO3
アイテム
Proton Therapy for Primary Renal Cell Carcinoma: The First Nationwide Retrospective Study in Japan
https://repo.qst.go.jp/records/80677
https://repo.qst.go.jp/records/80677a9bd06a9-cc10-48fc-8c72-033cc9332ae0
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-10-08 | |||||
| タイトル | ||||||
| タイトル | Proton Therapy for Primary Renal Cell Carcinoma: The First Nationwide Retrospective Study in Japan | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
FUKUMITSU, NOBUYOSHI
× FUKUMITSU, NOBUYOSHI× Ishikawa, Hitoshi× ARIMURA, TAKESHI× WADA, HITOSHI× Okimoto, Tomoaki× Satou, Yoshitaka× Iwata, Hiromitsu× SHIMIZU, SHOSEI× Sakurai, Hideyuki× Hitoshi, Ishikawa× Tomoaki, Okimoto× Yoshitaka, Satou× Hiromitsu, Iwata× Hideyuki, Sakurai |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background/aim: This multi-institutional study aimed to investigate the efficacy and feasibility of proton beam therapy (PBT) for renal cell carcinoma (RCC) in Japan. Patients and methods: The survival, local control, and toxicities in 22 RCC patients treated between 2001 and 2016 at 6 Japanese PBT institutes were analyzed. Results: The 22 patients comprised 20 men and had a median age of 67 (range=42-88) years. The total irradiation dose was 60-79.6 Gy (relative biological effectiveness). Over a median follow-up of 37 months, the 3-year overall and disease-specific survival rates were 95% and 100%, respectively, and no recurrence occurred. No patient experienced grade 3 or higher adverse events. The serum blood urea nitrogen (p=0.25) and creatinine levels (p=0.95) were not significantly affected, although the mean estimated glomerular filtration rate was reduced by 7.1±11.2 ml/min/1.73 m2 Conclusion: Despite the small number of patients, high-dose PBT can control RCC while maintaining their renal function with high probability, and could be and alternative curative therapy especially for inoperable patients. |
|||||
| 書誌情報 |
in vivo 巻 34, 号 5, p. 2883-2889, 発行日 2020-10 |
|||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0258-851X | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 32871828 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.21873/invivo.12116 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://iv.iiarjournals.org/content/34/5/2883.full | |||||
