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Biophysical Model Including a Potentially Lethal Damage Repair Parameter in Fractionated Carbon Beam
https://repo.qst.go.jp/records/80610
https://repo.qst.go.jp/records/806106f9d6a63-b9a9-47a4-83b3-c01c4898a12c
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-09-30 | |||||
タイトル | ||||||
タイトル | Biophysical Model Including a Potentially Lethal Damage Repair Parameter in Fractionated Carbon Beam | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Choi, Eunae
× Choi, Eunae× Yoon, Myonggeun× Suzuki, Masao× Matsufuji, Naruhiro× Jung, Wonguyn× Masao, Suzuki× Naruhiro, Matsufuji |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The amount of potentially lethal damage repair (PLDR) is a significant factor in the process of modeling the survival curves of cells irradiated with fractionated carbon beams. Because the amount of PLDR generally depends on the features of the cells and the linear energy transfer (LET), the amount of PLDR of cells irradiated with fractionated carbon beams shows distinct differences from that of cells irradiated with X-rays. This study considered a new parameter dependent on the correlation between the PLDR trait (T) of the cells over a time interval (Δ) at the fractionated carbon beam irradiation. The survival curves of the cells irradiated with fractionated carbon beams n times were predicted using the ζ and the Ψ values from the delay assay. This study aims to overcome the barriers of traditional methods by developing a new survival curve model with new parameters based on an analysis of the PLDR traits of cells over time interval in fractionated carbon beam irradiation and to suggest a model that produces results significantly closer to the experimental data. | |||||
書誌情報 |
Journal of the Korean Physical Society 巻 77, p. 161-167, 発行日 2020-09 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0374-4884 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3938/jkps.77.161 | |||||
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識別子タイプ | URI | |||||
関連識別子 | https://link.springer.com/article/10.3938/jkps.77.161 |