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Nucleosome unwrapping and unstacking
https://repo.qst.go.jp/records/80116
https://repo.qst.go.jp/records/801161e90f3bc-a333-47ca-afcd-4c623a749f71
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-06-29 | |||||
| タイトル | ||||||
| タイトル | Nucleosome unwrapping and unstacking | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kono, Hidetoshi
× Kono, Hidetoshi× Ishida, Hisashi× Kono, Hidetoshi× Ishida, Hisashi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Access to the eukaryotic genome is key to the regulation of such DNA processes as transcription, replication and repair. About three quarters of the human genome is stored and shielded within arrays of nucleosomes, the fundamental structural units of chromatin, each of which contains about 150 bp of DNA and an octameric histone protein composed of two each of H2A, H2B, H3 and H4. Structural fluctuation of nucleosomes provides regulatory proteins with transient access to the internal DNA; however, nucleosome unwrapping, sliding and unstacking must occur to obtain full access of the DNA. In this review, we focus on the unwrapping of mononucleosomes and internucleosomal interactions to discuss our current understanding of the dynamics of the process. | |||||
| 書誌情報 |
Current Opinion in Structural Biology 巻 64, p. 119-125, 発行日 2020-10 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0959-440X | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.sbi.2020.06.020 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.sciencedirect.com/science/article/pii/S0959440X20301196 | |||||
