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  1. 原著論文

Treatment effects on neurometabolite levels in schizophrenia: A meta-analysis dataset of proton magnetic resonance spectroscopy

https://repo.qst.go.jp/records/80111
https://repo.qst.go.jp/records/80111
fc393364-4c8e-4867-a7b1-fd1440b02824
Item type 学術雑誌論文 / Journal Article(1)
公開日 2020-06-25
タイトル
タイトル Treatment effects on neurometabolite levels in schizophrenia: A meta-analysis dataset of proton magnetic resonance spectroscopy
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Kubota, Manabu

× Kubota, Manabu

WEKO 890564

Kubota, Manabu

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Moriguchi, Sho

× Moriguchi, Sho

WEKO 890565

Moriguchi, Sho

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Takahata, Keisuke

× Takahata, Keisuke

WEKO 890566

Takahata, Keisuke

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Nakajima, Shinichiro

× Nakajima, Shinichiro

WEKO 890567

Nakajima, Shinichiro

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Horita, Nobuyuki

× Horita, Nobuyuki

WEKO 890568

Horita, Nobuyuki

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Kubota, Manabu

× Kubota, Manabu

WEKO 890569

en Kubota, Manabu

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Moriguchi, Sho

× Moriguchi, Sho

WEKO 890570

en Moriguchi, Sho

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Takahata, Keisuke

× Takahata, Keisuke

WEKO 890571

en Takahata, Keisuke

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抄録
内容記述タイプ Abstract
内容記述 This article describes a dataset for a meta-analysis that aimed to investigate the effects of treatment on the neurometabolite status in patients with schizophrenia (DOI of original article: https://doi.org/10.1016/j.schres.2020.03.069 [1]). The data search was performed with MEDLINE, Embase, and PsycINFO. The neurometabolites investigated include glutamate, glutamine, glutamate + glutamine, gamma-aminobutyric acid, N-acetylaspartate, and myo-inositol, and the regions of interest (ROIs) include the frontal cortex, temporal cortex, parieto-occipital cortex, thalamus, basal ganglia, and hippocampus. The meta-analysis was conducted with a random-effects model, and the use of the standardized mean difference method between pre- and post-treatment of subjects for neurometabolites in each ROI of three patient groups or more. The dataset covers raw data of 39 patient groups (773 patients with schizophrenia at follow-up) with neurometabolite levels measured by magnetic resonance spectroscopy both before and after treatment. Furthermore, it contains details of clinical characteristics and treatment types for each group. Therefore, the data would be useful for a reinvestigation of treatment effects on the neurometabolite status from diverse points of view, as well as for the development of future treatment strategies for psychiatric diseases.
書誌情報 Data in Brief

巻 31, p. 105862, 発行日 2020-06
ISSN
収録物識別子タイプ ISSN
収録物識別子 2352-3409
PubMed番号
識別子タイプ PMID
関連識別子 32637482
DOI
識別子タイプ DOI
関連識別子 10.1016/j.dib.2020.105862
関連サイト
識別子タイプ URI
関連識別子 https://www.sciencedirect.com/science/article/pii/S2352340920307563
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