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Whole gamma imaging: a new concept of PET combined with Compton
https://repo.qst.go.jp/records/80098
https://repo.qst.go.jp/records/80098cddc2521-31f4-49dd-a36f-c17ab7eb2ff7
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-06-19 | |||||
| タイトル | ||||||
| タイトル | Whole gamma imaging: a new concept of PET combined with Compton | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Yoshida, Eiji
× Yoshida, Eiji× Tashima, Hideaki× Nagatsu, Kotaro× Tsuji, Atsushi× Kamada, Kei× Parodi, Katia× Yamaya, Taiga× Yoshida, Eiji× Tashima, Hideaki× Nagatsu, Kotaro× Tsuji, Atsushi× Parodi, Katia× Yamaya, Taiga |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We proposed a concept of whole gamma imaging (WGI) that utilizes all detectable gamma rays for imaging. An additional detector ring, which is used as the scatterer, is inserted in the field-of-view of a PET ring so that single gamma rays can be detected by the Compton imaging method. In particular, for the non-pure positron emitters which emit an additional gamma ray almost at the same time, triple gamma imaging will be enabled; localization on each line-of-response (LOR) is possible by using the Compton cone of the additional gamma ray. We developed a prototype to show a proof of the WGI concept. The diameters of scatterer ring and PET ring were set as 20 cm and 66 cm, respectively. For Compton imaging of the 662-keV gamma ray from a 137Cs point source, spatial resolution obtained by the list-mode OSEM algorithm was 4.4 mm FWHM at the 8 cm off-center position and 13.1 mm FWHM at the center position. For PET imaging of a 22Na point source, spatial resolution was about 2 mm FWHM at all positions. For the triple gamma imaging, 5.7 mm FWHM (center) and 4.8 mm FWHM (8 cm off-center) were obtained for the 22Na point source just by plotting the intersecting points between each LOR and each Compton cone of the 1275-keV gamma ray. No image reconstruction was applied. Scandium-44 was produced as a practical candidate of the non-pure positron emitters, and 6.6 mm FWHM (center) and 5.8 mm FWHM (8 cm off-center) were obtained in the same manner. This direct imaging approach which neither requires time-consuming event integration nor iterative image reconstruction may allow in vivo real-time tracking of a tiny amount of activity. Our initial results showed the feasibility of the WGI concept, which is a novel combination of PET and Compton imaging. |
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| 書誌情報 |
Physics in Medicine & Biology 巻 65, 号 12, p. 125013-1-125013-15, 発行日 2020-06 |
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| 出版者 | ||||||
| 出版者 | IOP Publishing | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0031-9155 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1088/1361-6560/ab8e89 | |||||
| 関連サイト | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1088/1361-6560/ab8e89 | |||||
