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Detection of the usual interstitial pneumonia pattern in chest CT: effect of computer-aided diagnosis on radiologist diagnostic performance
https://repo.qst.go.jp/records/80050
https://repo.qst.go.jp/records/800505d5778cf-2ccf-405a-b050-63f4f0b4490b
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-06-10 | |||||
タイトル | ||||||
タイトル | Detection of the usual interstitial pneumonia pattern in chest CT: effect of computer-aided diagnosis on radiologist diagnostic performance | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Ryo, Fujita,
× Ryo, Fujita,× Tae, Iwasawa,× Iwao, Yuma× Takashi, Ogura,× Daisuke, Utsunomiya,× Iwao, Yuma |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background Anti-fibrotic drugs for interstitial pulmonary fibrosis (IPF) have been developed. Physicians are becoming increasingly aware of the need for better diagnosis of IPF. Purpose To evaluate whether a computer-aided system can improve the diagnostic performance of general radiologists in detecting the usual interstitial pneumonia (UIP) pattern on computed tomography (CT). Material and Methods We included 60 CT datasets from 30 patients with IPF and 30 with idiopathic fibrosing non-specific interstitial pneumonia (fNSIP), all diagnosed by a multidisciplinary diagnosis (MDD) procedure that included surgical biopsy. We analyzed the CT data using a computer-aided system (Gaussian histogram normalized correlation: GHNC). Five general radiologists with <6 years of experience each interpreted these CT scans with and without the GHNC results. We compared the likelihoods of a UIP-pattern diagnosis with the likelihood of the same diagnosis by MDD using the average area under the curve (AUC) of the receiver operating characteristics (ROC). We also evaluated the association between the radiologists’ diagnosis and survival using the Kaplan–Meier method. Results In the ROC analysis, the AUC increased significantly from 0.731 without GHNC to 0.829 with GHNC (P = 0.0396). The diagnosis without GHNC was not significantly associated with survival for any radiologist, but the UIP diagnosis with GHNC was significantly associated with a worse prognosis for four out of five radiologists. Conclusion The computer-aided system could increase the confidence level of UIP-pattern diagnosis by non-expert radiologists. |
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書誌情報 |
Acta Radiologica 発行日 2020-02 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0284-1851 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1177/0284185120902393 | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://journals.sagepub.com/doi/abs/10.1177/0284185120902393 |