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Detection of the usual interstitial pneumonia pattern in chest CT: effect of computer-aided diagnosis on radiologist diagnostic performance

https://repo.qst.go.jp/records/80050
https://repo.qst.go.jp/records/80050
5d5778cf-2ccf-405a-b050-63f4f0b4490b
Item type 学術雑誌論文 / Journal Article(1)
公開日 2020-06-10
タイトル
タイトル Detection of the usual interstitial pneumonia pattern in chest CT: effect of computer-aided diagnosis on radiologist diagnostic performance
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Ryo, Fujita,

× Ryo, Fujita,

WEKO 870728

Ryo, Fujita,

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Tae, Iwasawa,

× Tae, Iwasawa,

WEKO 870729

Tae, Iwasawa,

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Iwao, Yuma

× Iwao, Yuma

WEKO 870730

Iwao, Yuma

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Takashi, Ogura,

× Takashi, Ogura,

WEKO 870731

Takashi, Ogura,

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Daisuke, Utsunomiya,

× Daisuke, Utsunomiya,

WEKO 870732

Daisuke, Utsunomiya,

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Iwao, Yuma

× Iwao, Yuma

WEKO 870733

en Iwao, Yuma

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抄録
内容記述タイプ Abstract
内容記述 Background
Anti-fibrotic drugs for interstitial pulmonary fibrosis (IPF) have been developed. Physicians are becoming increasingly aware of the need for better diagnosis of IPF.

Purpose
To evaluate whether a computer-aided system can improve the diagnostic performance of general radiologists in detecting the usual interstitial pneumonia (UIP) pattern on computed tomography (CT).

Material and Methods
We included 60 CT datasets from 30 patients with IPF and 30 with idiopathic fibrosing non-specific interstitial pneumonia (fNSIP), all diagnosed by a multidisciplinary diagnosis (MDD) procedure that included surgical biopsy. We analyzed the CT data using a computer-aided system (Gaussian histogram normalized correlation: GHNC). Five general radiologists with <6 years of experience each interpreted these CT scans with and without the GHNC results. We compared the likelihoods of a UIP-pattern diagnosis with the likelihood of the same diagnosis by MDD using the average area under the curve (AUC) of the receiver operating characteristics (ROC). We also evaluated the association between the radiologists’ diagnosis and survival using the Kaplan–Meier method.

Results
In the ROC analysis, the AUC increased significantly from 0.731 without GHNC to 0.829 with GHNC (P = 0.0396). The diagnosis without GHNC was not significantly associated with survival for any radiologist, but the UIP diagnosis with GHNC was significantly associated with a worse prognosis for four out of five radiologists.

Conclusion
The computer-aided system could increase the confidence level of UIP-pattern diagnosis by non-expert radiologists.
書誌情報 Acta Radiologica

発行日 2020-02
ISSN
収録物識別子タイプ ISSN
収録物識別子 0284-1851
DOI
識別子タイプ DOI
関連識別子 10.1177/0284185120902393
関連サイト
識別子タイプ URI
関連識別子 https://journals.sagepub.com/doi/abs/10.1177/0284185120902393
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