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Long-term outcomes of skull base chordoma treated with high-dose carbon-ion radiotherapy.
https://repo.qst.go.jp/records/79995
https://repo.qst.go.jp/records/799957226b7c8-24e3-4cf4-886a-721c381b617e
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-06-01 | |||||
| タイトル | ||||||
| タイトル | Long-term outcomes of skull base chordoma treated with high-dose carbon-ion radiotherapy. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Koto, Masashi
× Koto, Masashi× Ikawa, Hiroaki× Kaneko, Takashi× Hagiwara, Yasuhito× Hayashi, Kazuhiko× Tsuji, Hiroshi× Koto, Masashi× Ikawa, Hiroaki× Kaneko, Takashi× Hagiwara, Yasuhito× Hayashi, Kazuhiko× Tsuji, Hiroshi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Abstract Background: We evaluated the long-term efficacy and safety of carbon-ion radiotherapy (C-ion RT) for skull base chordoma, a rare neoplasm. Methods: Thirty-four patients with skull base chordoma who were treated with C-ion RT were prospectively enrolled and analyzed retrospectively. C-ion RT was delivered with 60.8 Gy (relative biological effectiveness [RBE]) in 16 fractions at four fractions per week. Results: The median follow-up period was 108 months. The 5- and 9-year local control rates were 76.9% and 69.2%, respectively. The 5- and 9-year overall survival rates were 93.5% and 77.4%, respectively. Regarding grade 3 or more severe late reactions, one patient developed a grade 3 mucosal ulcer, two developed grade 4 ipsilateral optic nerve injuries, and one developed a grade 5 mucosal ulcer at 9 years and 3 months after C-ion RT. Conclusion: C-ion RT with 60.8 Gy (RBE)/16 fractions is a promising treatment option for inoperable skull base chordoma. |
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| 書誌情報 |
Head & neck 巻 42, 号 9, p. 2607-2613, 発行日 2020-05 |
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| 出版者 | ||||||
| 出版者 | John Wiley And Sons | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1043-3074 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 32472716 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1002/hed.26307 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://onlinelibrary.wiley.com/doi/full/10.1002/hed.26307 | |||||
