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マイクロビームと組織培養を用いた放射線組織生物学―保健物理学と放射線生物学の接点として
https://repo.qst.go.jp/records/79115
https://repo.qst.go.jp/records/791150a92d5da-0f57-4416-b020-afb403f506ec
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-03-02 | |||||
| タイトル | ||||||
| タイトル | マイクロビームと組織培養を用いた放射線組織生物学―保健物理学と放射線生物学の接点として | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
福永, 久典
× 福永, 久典× 横谷, 明徳× Yokoya, Akinari |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | As a complex system, tissue has a highly dynamic structure to maintain a stable internal environment and such homeostasis mechanisms could be involved in radiation-induced biological responses at the tissue level. In fact, tissue-weighting factors have been regarded as an essential index for the guideline released from the International Committee on Radiological Protection. The illustrations of the applications of microbeams and tissue cultures in this article focus on their relevance to radiobiology and health physics, demonstrating the importance of synergy in the radiation sciences. In addition, we show an application of an ex vivo mouse testicular tissue culture as an experimental model of spermatogenesis to investigate the radiobiological effects with X-ray microbeams. Our model represents a unique application in the field, which offers significant potential for gaining further mechanistic insight into radiation biological effects at the tissue level and appropriate radiological protection. The viewpoint of radiation tissue biology will provide a novel approach for more accurate risk assessment of radiation exposures. | |||||
| 書誌情報 |
保健物理 巻 55, 号 2, p. 92-96, 発行日 2020-07 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0367-6110 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.5453/jhps.55.92 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.jhps.or.jp/upimg/files/55-2-WEB-final.pdf.pdf | |||||
