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Self-Assembly of Constrained Cyclic Peptides Controlled by Ring Size
https://repo.qst.go.jp/records/79071
https://repo.qst.go.jp/records/790711cc51fae-596a-434c-bd05-e087629d4a66
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-02-26 | |||||
| タイトル | ||||||
| タイトル | Self-Assembly of Constrained Cyclic Peptides Controlled by Ring Size | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kuan, Hu
× Kuan, Hu× Xiong, Wei× Sun, Chengjie× Wang, Chan× Li, Jingxu× Yin, Feng× Jiang, Yixiang× Ming-Rong, Zhang× Li, Zhou× Wang, Xinwei× Li, Zigang× Kuan, Hu× Zhang, Ming-Rong |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The de novo design of new peptide assemblies that expands the repertoire of biomaterial nanostructures has been of a tremendous challenge. Hence, it is evident that a successful research achievement in this area would increase the understanding of molecular interactions in supramolecules and create novel scaffolds exploitable in biotechnology and synthetic biology. The manipulation of cyclic peptide self-assembly is particularly intriguing for this purpose. Herein, we report that a novel type of cyclic peptides, referred to as chiral tether constrained cyclic peptides (CCP), shows promising self-assembly properties. CCPs are the first example of a controllable assembly of all-L-α-cyclic peptides with different ring sizes. A noteworthy feature of the CCP system is good tolerance of different secondary structures, ring size, and peptide sequence. Based on this system, a variety of nanostructures could be constructed, which display different physical properties, rendering it an excellent platform for molecular interaction studies. Further, demonstrate potential applications of these peptide assemblies in bioimaging and energy storage. | |||||
| 書誌情報 |
CCS Chemistry 巻 2, 号 1, p. 42-51, 発行日 2020-02 |
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| 出版者 | ||||||
| 出版者 | CHINESE CHEMICAL SOCIETY PUBLISHING | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2096-5745 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.31635/ccschem.020.201900047 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.chinesechemsoc.org/doi/10.31635/ccschem.020.201900047 | |||||
