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Efficacy and Feasibility of Salvage Re-Irradiation with CyberKnife for In-Field Neck Lymph Node Recurrence: A Retrospective Study
https://repo.qst.go.jp/records/79023
https://repo.qst.go.jp/records/790233995193b-5389-4770-b280-24b9b6750a1b
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-02-20 | |||||
タイトル | ||||||
タイトル | Efficacy and Feasibility of Salvage Re-Irradiation with CyberKnife for In-Field Neck Lymph Node Recurrence: A Retrospective Study | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Kobayashi, Daijiro
× Kobayashi, Daijiro× Sato, Hiro× Jun-ichi, Saitoh× Oike, Takahiro× Nakajima, Atsushi× Shin-ei, Noda× Kato, Shingo× Iwanaga, Mototaro× Shimizu, Tsuneo× Nakano, Takashi× Nakano, Takashi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Neck lymph node (LN) recurrence in the irradiated field represents an important aspect of treatment failure after primary radiotherapy owing to the lack of a standard treatment. The aim of this study is to investigate the efficacy and safety of CyberKnife treatment for neck LN recurrence after radiotherapy. Between 2008 and 2016, 55 neck LN recurrences after radiotherapy in 16 patients were treated with CyberKnife. The median follow-up period was 17 months (range, 2–53 months). The median previous radiotherapy dose was 68 Gy (range, 50–70 Gy). The median marginal dose as equivalent dose delivered in 2-Gy fractions (α/β = 10) was 50 Gy (range, 40–58 Gy). The one-year local control (LC) and overall survival rates were 81% and 71%, respectively. The one-year LC was higher with a target volume ≤1.0 cm3 than that with a target volume >1.0 cm3 (p = 0.006). Fatal bleeding was observed in one patient who had large (91 cm3) and widespread tumor with invasion to the carotid artery before CyberKnife treatment. CyberKnife treatment for neck LN recurrence is safe and feasible in most cases. Indication for the treatment should be carefully considered for large and widespread tumors. | |||||
書誌情報 |
Journal of Clinical Medicine 巻 8, 号 11, 発行日 2019-11 |
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出版者 | ||||||
出版者 | MDPI | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2077-0383 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3390/jcm8111911 | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.mdpi.com/2077-0383/8/11/1911 |