WEKO3
アイテム
Modified NEMA NU-2 performance evaluation methods for a brain-dedicated PET system with a hemispherical detector arrangement
https://repo.qst.go.jp/records/78125
https://repo.qst.go.jp/records/781250051b042-f003-445d-9c07-7b69938d1194
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-12-20 | |||||
| タイトル | ||||||
| タイトル | Modified NEMA NU-2 performance evaluation methods for a brain-dedicated PET system with a hemispherical detector arrangement | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Akamatsu, Go
× Akamatsu, Go× Tashima, Hideaki× Yoshida, Eiji× Wakizaka, Hidekatsu× Iwao, Yuma× Maeda, Takamasa× Takahashi, Miwako× Yamaya, Taiga× Go, Akamatsu× Hideaki, Tashima× Eiji, Yoshida× Hidekatsu, Wakizaka× Yuma, Iwao× Takamasa, Maeda× Miwako, Takahashi× Taiga, Yamaya |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Brain PET imaging has important roles in neurology, neuro-oncology and molecular imaging research. We have developed a helmet-type PET prototype and have shown that the proposed hemispherical geometry had high potential for realizing high-sensitivity and low-cost brain imaging. However, there is no standard performance evaluation method for helmet-type PET, which would be a bottleneck to its commercialization. Therefore, we investigated appropriate performance evaluation methods for a helmet-type PET based on the NEMA NU 2-2018 standards. For those measurement methods that are not applicable to the helmet-type PET, we changed them while keeping the basic concept of the original NEMA standards. We measured spatial resolution, sensitivity, scatter fraction, count rate characteristics, accuracy of corrections for count losses and randoms, and image quality. We partially changed the measurement methods by making brain-size phantoms and by optimizing the length or the position of radioactive sources. The spatial resolution was 2.8 mm at 1-cm offset position by the filtered back-projection method. Sensitivities measured by the NEMA original setup and the proposed setup were 13.4 and 57.1 kcps/MBq. The respective values measured with our developed brain-size scatter phantom and with the conventional whole-body-size scatter phantom were: scatter fractions of 35% and 35%; peak NECRs of 25.1 kcps at 3.2 kBq/ml and 19.8 kcps at 2.6 kBq/ml; and maximum absolute biases of 5.5% and 16.0%. The image quality was evaluated with the developed brain-size phantom, and good image quality was obtained. The helmet-type PET prototype showed high-sensitivity even with the small number of 54 detectors. The spatial resolution was better than 4.0 mm over the field-of-view. In conclusion, we proposed the performance evaluation methods for a brain-dedicated PET system with a hemispherical geometry. The proposed method could facilitate evaluation of performance characteristics of brain-dedicated PET scanners and optimization of its scanning and reconstruction parameters. |
|||||
| 書誌情報 |
Biomedical Physics & Engineering Express 巻 6, 号 1, p. 015012, 発行日 2020-01 |
|||||
| 出版者 | ||||||
| 出版者 | IOP publishing | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2057-1976 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1088/2057-1976/ab5c05 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://iopscience.iop.org/article/10.1088/2057-1976/ab5c05 | |||||
