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Quantitative estimation of absorbed dose of emitted particles from Cu-64 aqueous solution using FNTD

https://repo.qst.go.jp/records/77821
https://repo.qst.go.jp/records/77821
a74ac1b0-383e-4d5d-a148-5771db4819b2
Item type 会議発表用資料 / Presentation(1)
公開日 2019-12-06
タイトル
タイトル Quantitative estimation of absorbed dose of emitted particles from Cu-64 aqueous solution using FNTD
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Kusumoto, Tamon

× Kusumoto, Tamon

WEKO 1070805

Kusumoto, Tamon

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Hasegawa, Sumitaka

× Hasegawa, Sumitaka

WEKO 1070806

Hasegawa, Sumitaka

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Ogawara, Ryo

× Ogawara, Ryo

WEKO 1070807

Ogawara, Ryo

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S Akserlod, Mark

× S Akserlod, Mark

WEKO 1070808

S Akserlod, Mark

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Kodaira, Satoshi

× Kodaira, Satoshi

WEKO 1070809

Kodaira, Satoshi

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Tamon, Kusumoto

× Tamon, Kusumoto

WEKO 1070810

en Tamon, Kusumoto

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Ryo, Ogawara

× Ryo, Ogawara

WEKO 1070811

en Ryo, Ogawara

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Satoshi, Kodaira

× Satoshi, Kodaira

WEKO 1070812

en Satoshi, Kodaira

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抄録
内容記述タイプ Abstract
内容記述 We report dose estimation of emitted particles from Cu-64 source using combination of Fluorescent Nuclear Track Detector (FNTD) and Monte Carlo simulations in the PHITS cone and Geant4 toolkit. The significantly high absorbed dose by Auger electrons is observed around the FNTD surface. Then, the absorbed dose monotonically reduces with increasing the depth of FNTD. The result of the PHITS code is exactly equivalent to that of Geant4. Also, the simulations are well agreement with experimental results. If the contribution of Auger electrons I ignored, the significantly high absorbed dose proximal to the source is not properly reduced. These findings demonstrate that Auger electrons work very effectively to kill cancer cells proximal to Cu-64 source while minimizing damage effects on normal cells distal to the source. At 15 μm where is men cell radius, the absorbed dose of eta particles is about 24% of that at FNTD surface. We soul take into account the contribution of free radical created by beta particles for clarifying the impact of Cu-64 on tissues.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 第3回QST国際シンポジウム「Quantum Life Science」参加
発表年月日
日付 2019-12-04
日付タイプ Issued
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