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Quantitative estimation of absorbed dose of emitted particles from Cu-64 aqueous solution using FNTD
https://repo.qst.go.jp/records/77821
https://repo.qst.go.jp/records/77821a74ac1b0-383e-4d5d-a148-5771db4819b2
Item type | 会議発表用資料 / Presentation(1) | |||||
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公開日 | 2019-12-06 | |||||
タイトル | ||||||
タイトル | Quantitative estimation of absorbed dose of emitted particles from Cu-64 aqueous solution using FNTD | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
資源タイプ | conference object | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Kusumoto, Tamon
× Kusumoto, Tamon× Hasegawa, Sumitaka× Ogawara, Ryo× S Akserlod, Mark× Kodaira, Satoshi× Tamon, Kusumoto× Ryo, Ogawara× Satoshi, Kodaira |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We report dose estimation of emitted particles from Cu-64 source using combination of Fluorescent Nuclear Track Detector (FNTD) and Monte Carlo simulations in the PHITS cone and Geant4 toolkit. The significantly high absorbed dose by Auger electrons is observed around the FNTD surface. Then, the absorbed dose monotonically reduces with increasing the depth of FNTD. The result of the PHITS code is exactly equivalent to that of Geant4. Also, the simulations are well agreement with experimental results. If the contribution of Auger electrons I ignored, the significantly high absorbed dose proximal to the source is not properly reduced. These findings demonstrate that Auger electrons work very effectively to kill cancer cells proximal to Cu-64 source while minimizing damage effects on normal cells distal to the source. At 15 μm where is men cell radius, the absorbed dose of eta particles is about 24% of that at FNTD surface. We soul take into account the contribution of free radical created by beta particles for clarifying the impact of Cu-64 on tissues. | |||||
会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 第3回QST国際シンポジウム「Quantum Life Science」参加 | |||||
発表年月日 | ||||||
日付 | 2019-12-04 | |||||
日付タイプ | Issued |