WEKO3
アイテム
Whole gamma imaging of 89Zr-injected mouse: comparison of PET and Compton imaging
https://repo.qst.go.jp/records/77352
https://repo.qst.go.jp/records/77352a070a4ba-8764-4887-bbfe-6920b5ebacda
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-07-17 | |||||
| タイトル | ||||||
| タイトル | Whole gamma imaging of 89Zr-injected mouse: comparison of PET and Compton imaging | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Tashima, Hideaki
× Tashima, Hideaki× Yoshida, Eiji× Wakizaka, Hidekatsu× Takahashi, Miwako× Nagatsu, Kotaro× Tsuji, Atsushi× Kamada, Kei× Parodi, Katia× Yamaya, Taiga× Tashima, Hideaki× Yoshida, Eiji× Wakizaka, Hidekatsu× Takahashi, Miwako× Nagatsu, Kotaro× Tsuji, Atsushi× Parodi, Katia× Yamaya, Taiga |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Whole gamma imaging (WGI) is our original idea to combine PET imaging and Compton imaging by inserting a scatterer ring into a PET ring. Not only PET nuclides but also various types of single gamma emitters can be imaged. In this work, for a proof-of-concept of WGI, we developed a scatterer ring (GAGG+MPPC, diameter of 94 mm), which was inserted into a PET ring (GSO+PMT, diameter of 660 mm). We demonstrated animal imaging to clarify one of the current technological limitations of Compton imaging in the WGI. We performed a 1-hour long acquisition for a mouse, 22 hours after injection of 9.8 MBq 89Zr oxalate. The 89Zr emits 909 keV gamma rays as well as positrons. Therefore, we can directly compare Compton imaging performance with PET imaging performance. As a result, we acquired both PET and single gamma images of the mouse, in which 89Zr assimilated in the bone. Although these images were well correlated, the spatial resolution of the single gamma image was inferior to the PET image and distorted. The distortion of the reconstructed image occurs due to mismatch between actual and modeled systems. The proof-of-concept showed the spatial resolution limitation of the current prototype for Compton imaging and the necessity for improving the system modeling to mitigate the distortion. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 2019 IEEE Nuclear Science Symposium and Medical Imaging Conference | |||||
| 発表年月日 | ||||||
| 日付 | 2019-11-02 | |||||
| 日付タイプ | Issued | |||||
