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X-Ray diffraction experiments for drug target protein of human casein kinase II
https://repo.qst.go.jp/records/77249
https://repo.qst.go.jp/records/772497506b6ac-7b0b-4ab0-ad67-a22efa54f464
| Item type | 会議発表論文 / Conference Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-06-26 | |||||
| タイトル | ||||||
| タイトル | X-Ray diffraction experiments for drug target protein of human casein kinase II | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
| 資源タイプ | conference paper | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Shibazaki, Chie
× Shibazaki, Chie× Arai, Shigeki× Shimizu, Rumi× Adachi, Motoyasu× Shibazaki, Chie× Arai, Shigeki× Shimizu, Rumi× Adachi, Motoyasu |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Casein kinase II (CKII) exhibits broad phosphorylation reaction on various important regulatory proteins such as survival factors in eukaryotic cells. Since the relationship of CKII over-expression to carcinogenesis and cancer metastasis has been reported, CKII is considered to be one of the drug target proteins. Here, we aimed to obtain the structural information with location of hydration water molecules, and to elucidate the catalytic reaction of CKII for development of effective inhibitors. | |||||
| 書誌情報 |
Photon Factory Activity Report 2018 巻 36, p. 149, 発行日 2019-06 |
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