WEKO3
アイテム
Total-Body Animal PET with a 4-Layer DOI Detector - GATE Simulation Study
https://repo.qst.go.jp/records/77146
https://repo.qst.go.jp/records/7714626c4b076-8c2a-4567-9fbf-96b4b93d4ff4
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-10-16 | |||||
| タイトル | ||||||
| タイトル | Total-Body Animal PET with a 4-Layer DOI Detector - GATE Simulation Study | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kang, Hangyu
× Kang, Hangyu× Tashima, Hideaki× Nishikido, Fumihiko× Yoshida, Eiji× Yamaya, Taiga× Kang, Hangyu× Tashima, Hideaki× Nishikido, Fumihiko× Yoshida, Eiji× Yamaya, Taiga |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Recently, the first total-body positron emission tomography (PET) scanner for high sensitivity clinical imaging was developed by a group led by Simon Cherry in UC Davis. However, the long axial FOV causes a parallax error not only in the radial direction but also in the axial direction, and these parallax errors must be mitigated. This can be done by using a depth-of-interaction (DOI) detector. The aim of this study is to investigate appropriate use of DOI detectors to mitigate the parallax errors in a long axial field-of-view PET scanner. The four-layer DOI detector originally developed for OpenPET and the helmet-type PET are reutilized to build an animal PET prototype as the first demonstration. The proposed total-body animal DOI PET scanner has an inner diameter of 120 mm and an axial length of 316 mm. The DOI PET detector consists of a 4-layer Zr-doped gadolinium oxyorthosilicate (GSOZ) crystal array and an 8×8 array multi-anode PMT. Each crystal layer has a 16×16 array of GSOZ crystals (2.8×2.8×7.5 mm3) which yield a total crystal thickness of 30 mm. The effect of DOI information on the PET image quality is investigated with grid patterned point sources by using GATE Monte Carlo simulation. The parallax error along the radial and axial directions can be reduced by using the 4-layer DOI detector. The total-body animal PET scanner based on the 4-layer DOI detector can provide a uniform spatial resolution of around 1.7 mm across the entire FOV. The peak sensitivity of 25% is obtained at the center of the FOV. In the future, we will develop a prototype total-body animal DOI PET scanner with our other existing 4-layer DOI detectors to demonstrate the usefulness of the DOI information for a long axial FOV PET scanner. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 2019 IEEE Nuclear Science Symposium and Medical Imaging Conference | |||||
| 発表年月日 | ||||||
| 日付 | 2019-10-31 | |||||
| 日付タイプ | Issued | |||||
