WEKO3
アイテム
Integrated approach of experimental data and computer modeling and simulation for understanding chromatin structure and dynamics
https://repo.qst.go.jp/records/76968
https://repo.qst.go.jp/records/76968b9024e7c-b748-463a-a13b-7501a51a6ddb
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-09-30 | |||||
| タイトル | ||||||
| タイトル | Integrated approach of experimental data and computer modeling and simulation for understanding chromatin structure and dynamics | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kono, Hidetoshi
× Kono, Hidetoshi× Matsumoto, Atsushi× Sakuraba, Shun× Ishida, Hisashi× Kono, Hidetoshi× Matsumoto, Atsushi× Sakuraba, Shun× Ishida, Hisashi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | X-ray crystallographic analysis and single molecule analysis of electron microscopy provide us precise images of biomolecules, but the information is basically static. X-ray or neutron scattering give us structural information of the molecules in solution, but they are low resolution. We integrate such information with aids of computer modeling and simulation to build the 3D structures in solution and investigate the dynamics of mono- or di-nucleosome which are fundamental structural units of chromatin. We show that histone tails, which are difficult to experimentally see because of their nature of being in intrinsically disordered, are a key to stabilize various conformations. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第57回日本生物物理学会年会 | |||||
| 発表年月日 | ||||||
| 日付 | 2019-09-25 | |||||
| 日付タイプ | Issued | |||||
